Stability Constants of Complexes

The quantitative treatment of metal-ion coordination in biomolecules is a major challenge in biochemistry, which is usually quantified by stability constants. The stability constant is the equilibrium constant for the formation of complexes in solution. It is the measurement of the strength of the interaction between the reagent and the complex formed by aggregation on the reagent.

The stability constant provides necessary information for the calculation of complex concentration in solution, and it is also an important parameter for the study of receptor-ligand binding. Stability constants have a wide range of applications, for example, in biology, the study of stability constants of nucleic acids and ligands, proteins and enzymes and metals, as well as drugs and biomolecules plays an important role in organism poisoning and detoxification.

Alfa Chemistry has a professional analysis team and advanced instrumentation to meet the pharmaceutical industry's various testing services, no matter at what stage your pharmaceutical research is, Alfa Chemistry can provide you with the most comprehensive testing services. Our experts can customize personalized testing services according to your requirements when you are confused. In addition to the determination of stability constant, we can also provide a range of services for the testing of pharmaceutical physical and chemical properties. Please feel free to contact us if you need any testing services in your pharmaceutical research.

Alfa Chemistry provides a variety of test methods for stability constants, such as:

• Electrochemical Method

• Spectrophotometry Method

• High Performance Liquid Chromatography (HPLC)

• Affinity Capillary Electrophoresis (ACE)

Alfa Chemistry's physical characterization services of pharmaceutical include:

Alfa Chemistry's advantages:

Reference

• Gutten O. (2013) 'Predicting the stability constants of metal-ion complexes from first principles.' Inorg Chem. 52(18):10347-55.