LA8080 High Speed Amino Acid Analyzer, Hitachi

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Note: this service is for Research Use Only and Not intended for clinical use.

The Hitachi LA8080 High Speed Amino Acid Analyzer combines the robustness of Hitachi liquid chromatography systems with a high-performance post-column ninhydrin reaction technology to deliver precise and stable amino acid analysis. Designed for biochemical, food, and biopharmaceutical applications, the system provides reliable quantification of amino acid profiles across a wide range of sample types. Its stable reaction control and high-sensitivity detection make it suitable for both routine testing and advanced analytical workflows.

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Key FeaturesTechnical SpecificationsSystem PerformanceApplications

Post-column ninhydrin reaction system optimized for stable amino acid detection
Improved operational accessibility for routine maintenance and workflow efficiency
Enhanced safety design with optimized leak sensor positioning
High-stability reaction control ensuring accurate protein hydrolysate analysis
Ion-exchange chromatography compatibility for diverse amino acid methods

Parameter	Specification
Column	4.6 mm ID × 60 mm, Hitachi custom ion-exchange resin
Pump Flow Rate	0.001 – 1.000 mL/min
Discharge Pressure	0 – 34 MPa
Gradient System	6-solution gradient elution
Autosampler	Direct injection, up to 120 vials (100 with cooling)
Injection Volume	0.5 – 100 µL
Column Oven	Peltier system, 20 – 90 °C (1 °C increments)
Reaction Unit	Electronic heating, 50 – 140 °C (1 °C increments)
Detector	Aberration-corrected spectrophotometer
Detection Wavelength	570 nm / 440 nm

Parameter	Protein Hydrolysate Analysis	Physiological Fluid Analysis
Analysis Time	Approx. 30 min (net)	Approx. 110 min (net)
Resolution	Thr–Ser, Gly–Ala, Ile–Leu ≥ 1.2	Thr–Ser, Gly–Ala, Ile–Leu ≥ 1.2
Retention Time Reproducibility	RSD ≤ 0.5% (Ala), ≤ 0.3% (Arg)	RSD ≤ 0.5% (Ala), ≤ 0.3% (Arg)
Peak Area Reproducibility	RSD ≤ 1.0% (Gly, His)	RSD ≤ 1.5% (Gly, His)
Detection Limit	2.5 pmol (S/N = 2 at Asp peak)	8 pmol (S/N = 2 at Asp peak)

The LA8080 is widely used for amino acid profiling and biochemical analysis across multiple fields, including but not limited to:

Food and beverage analysis (umami components, nutritional profiling)
Biopharmaceutical quality control (protein-based therapeutics)
Health supplement testing (active ingredient evaluation)
Protein hydrolysate and physiological fluid analysis
Ion-exchange amino acid separation studies
Research and regulated biochemical testing

The LA8080 High Speed Amino Acid Analyzer strengthens laboratory's biochemical analysis capabilities by providing accurate and reproducible amino acid quantification based on a stable post-column ninhydrin reaction system. Its compact design, high-sensitivity detection, and robust ion-exchange chromatography compatibility enable reliable analysis of complex biological and food samples, supporting high-quality testing services across pharmaceutical, food, and life science applications.

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