The Thermo Scientific Titan Krios G3i is a state-of-the-art cryogenic transmission electron microscope designed for high-resolution structural biology and molecular imaging. Built on a highly stable 300 kV transmission electron microscope platform, the system combines advanced automation, intelligent workflow management, and high-throughput data acquisition to support demanding cryo-electron microscopy applications. Its integrated cryogenic Autoloader enables secure, contamination-free sample handling, while automated alignments and guided operation simplify complex experimental procedures. By seamlessly connecting sample preparation, image acquisition, and data processing, the Titan Krios G3i provides researchers with a reliable platform for obtaining high-quality structural data with exceptional efficiency and reproducibility.
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- Thermo Scientific Titan Krios G3i Cryo-TEM
Thermo Scientific Titan Krios G3i Cryo-TEM
InquiryThrough our global network of testing experts and analytical equipment including chromatography (HPLC, GC, GC/MS) and atomic absorption spectroscopy (AAS, GFA, FIAS), Our goal is to provide test services as efficiently as possible to maximize our customers' profits. For more information about our services, contact one of our experts today.
Note: this service is for Research Use Only and Not intended for clinical use.
Key FeaturesTechnical SpecificationsApplications
- Highly stable 300 kV X-FEG electron optical platform for high-resolution cryo-EM imaging.
- Intelligent automation with automated alignments and guided operation through the integrated EPU software interface.
- Cryogenic Autoloader capable of handling up to 12 sample grids for high-throughput operation.
- Optimized optical performance with continuous system self-assessment and automated microscope alignment.
- Seamless workflow connectivity supporting contamination-free sample transfer between compatible Autoloader-equipped Cryo-TEM systems.
- High-resolution imaging with reduced thermal drift and minimized linear distortion.
- Efficient batch screening, automated atlas generation, and guided grid selection to accelerate data collection.
- Dedicated single-axis cryo-tomography holder with improved eucentric performance for accurate tilt-series acquisition.
- 300 kV X-FEG
- Cryogenic Autoloader (up to 12 grids)
- Gatan K3 Direct Detector
- Gatan BioQuantum Image Filter
- Ceta 16M Camera
- Falcon 3EC Detector
- Parallel Illumination
- Phase Plate
- Single-axis tilt holder (±70°)
- Automated data collection
The Thermo Scientific Titan Krios G3i Cryo-TEM is widely used for high-resolution structural analysis of biological macromolecules and complex molecular assemblies in their near-native states. It is particularly suited for single-particle analysis (SPA), enabling three-dimensional reconstruction of proteins, protein complexes, viruses, and other biomolecular structures at near-atomic resolution. The system also supports cryo-electron tomography (Cryo-ET) for visualizing cellular architectures and macromolecular interactions within intact cells and tissues. In addition, it provides powerful capabilities for structural biology, pharmaceutical research, vaccine development, virology, and biomolecular mechanism studies, helping researchers investigate biological processes at the molecular level with outstanding accuracy and efficiency.
The addition of the Thermo Scientific Titan Krios G3i Cryo-TEM significantly strengthens advanced structural characterization capabilities for life science and biomedical research. Its combination of automated cryogenic sample handling, high-resolution imaging, intelligent workflow integration, and high-throughput data acquisition delivers reliable and reproducible cryo-electron microscopy analyses for challenging biological samples, supporting academic research, biotechnology, pharmaceuticals and innovative biomedical development.
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