Bruker ultrafleXtreme MALDI-TOF

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Note: this service is for Research Use Only and Not intended for clinical use.

The Bruker ultrafleXtreme is a high-performance MALDI-TOF/TOF mass spectrometer designed for rapid and accurate large molecular analysis. Equipped with Bruker's proprietary smartbeam-II™ laser and advanced TOF/TOF technology, the system enables both MS and MS/MS experiments at high acquisition speeds while maintaining excellent sensitivity and mass accuracy. Its broad mass range, high resolution, and robust operation make it an ideal platform for proteomics, polymer characterization, glycoprotein analysis, microbial identification, and other advanced analytical workflows.

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Key FeaturesTechnical SpecificationsApplications

• The patented smartbeam-II™ laser supports repetition rates from 1–2000 Hz, enabling rapid MS and MS/MS data collection while maintaining excellent analytical performance.
• The system delivers resolving power of up to 40,000 in reflector mode and mass accuracy down to 1 ppm, providing confident identification of complex biomolecules.
• With detection limits reaching the attomole (amol) level, the ultrafleXtreme enables reliable analysis of low-abundance analytes.
• An IR laser-based self-cleaning ion source and long-life laser design ensures high instrument uptime, stable performance, and reduced maintenance requirements.
• Integrated Bruker software supports efficient data processing, visualization, and interpretation.

Parameter	Specification
Mass Range	≥ 500,000 Da
Resolution (Linear Mode)	≥1,200 (at m/z 12,361)
Resolution (Reflector Mode)	> 40,000
Mass Accuracy (Internal Calibration)	≤ 1.5 ppm (Reflector Mode)
Sensitivity (Reflector Mode)	250 amol
Laser Repetition Rate	1–2000 Hz
Laser Lifetime	> 3.5 × 109 Pulses

• Advanced Peptide and Protein Analysis: The Bruker ultrafleXtreme is a powerful platform for proteomics research, enabling rapid identification and characterization of peptides, proteins, and glycoproteins. Its high mass accuracy, sensitivity, and MS/MS capabilities support peptide mass fingerprinting, protein sequencing, biomarker discovery, and biopharmaceutical characterization.
• Polymer Characterization: The system provides comprehensive polymer analysis, including determination of molecular weight distribution, number-average and weight-average molecular weights, degree of polymerization, dispersity, and end-group composition. It also supports the characterization of copolymers and complex polymer architectures, making it a valuable tool for polymer research, product development, and quality control.

The addition of the Bruker ultrafleXtreme significantly enhances laboratory mass spectrometry capabilities, enabling high-throughput and high-confidence molecular characterization across life sciences, materials science, biotechnology, and industrial research. By combining exceptional speed, sensitivity, and analytical performance, this platform delivers comprehensive data that supports product development, quality assurance, and advanced scientific investigations.

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