Solubility
Through our global network of testing experts and analytical equipment including chromatography (HPLC, GC, GC/MS) and atomic absorption spectroscopy (AAS, GFA, FIAS), Our goal is to provide test services as efficiently as possible to maximize our customers' profits. For more information about our services, contact one of our experts today.
Note: this service is for Research Use Only and Not intended for clinical use.
Solubility, the phenomenon of dissolution of solute in solvent to give a homogenous system, is one of the important parameters to achieve desired concentration of drug in systemic circulation for desired (anticipated) pharmacological response. Low aqueous solubility is the major problem encountered with formulation development of new chemical entities as well as for the generic development. More than 40% NCEs (new chemical entities) developed in pharmaceutical industry are practically insoluble in water. Solubility is a major challenge for formulation scientist. Any drug to be absorbed must be present in the form of solution at the site of absorption. [1]
As a global leading pharmaceutical analysis services company, Alfa Chemistry provides solubility characterization of preclinical candidate and other preformulation analysis services. Alfa Chemistry is the perfect partner for getting expertise, flexibility, and reliability with your pharmaceutical formulation project.
Alfa Chemistry's solubility characterization services include:
pH solubility profile
Solubility in organic solvents
Solubility in Fasted State Simulated Intestinal Fluid (FaSSIF), Fed State Simulated Intestinal Fluid (FeSSIF) and Simulated Gastric Fluid (SGF)
Alfa Chemistry's instrument platforms:
µDISS Profiler Small Volume Dissolution and Solubility Apparatus
µSOL Evolution/EVO 96 High Throughput Miniaturized Shake Flask Solubility
µSOL Explorer Miniaturized Shake Flask Solubility
Gemini Profiler Ionization and Lipophilicity Analyzer
Our advantages:
Short Detection Cycle
Competitive Price
Years of Experience
Professional Equipment
Reliable Results
Compliance with Various Standards
Reference
Savjani, K. T., Gajjar, A. K., & Savjani, J. K. (2012). Drug solubility: importance and enhancement techniques. ISRN pharmaceutics, 1-10.
Do not know how to place an order, please refer to the flow chart shown below.
Submit quotation request |
A technical manager will contact you within 24 hours |
You will review and approve the final price and place an order |
Confirm with you and make the payment |
Instruct you to ship your samples and form |
Analytic report delivery |
If you have questions at any time during the process, just give us a call or send us an email at . We will do all we can to meet your needs.
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