Safety Testing of Nano Products
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Nanomaterials are materials with special properties at least one dimension in the three-dimensional space (1 mm 100 nm), or composed of nanostructural units, which is regarded as "one of the most important strategic high-tech materials in the 21st century". Because of its structural particularity and extremely unstable state in thermodynamics, nanomaterials have special properties such as small size effect, surface effect, quantum size effect and macroscopic quantum tunneling effect. As well as many physical and chemical properties that traditional materials do not have, such as high chemical activity, strong adsorption, special catalysis, and so on. Nanomaterials and novel engineered nanotechnology offer great potential to improving the quality of life when used in applications across a variety of industries and consumer products. Today, it is widely used in medicine, manufacturing, materials, communications, biology, environment, energy, food and other fields.
To realise the full potential of your nanomaterial products, it is vital to understand the unique properties of these materials and to address potential safety or risk concerns for human health and the environment. Alfa Chemistry supports our clients' nanotechnology innovation with nanomaterial chemical testing, risk assessment and safety consulting.
Our professional testing solution spans sectors as diverse as:
Microelectronics, Electricity
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Our extensive nanomaterials and nanotechnology capabilities include:
Techniques for safety testing of nano products
Transmission Electron Microscope (TEM)
Transmission Electron Microscope (TEM) is an instrument that can observe nanoscale materials. It has a higher resolution and magnification power compared to conventional optical microscopes. TEM is composed of infrared ray transmission and electron diffraction technologies. Through the microscopic images of the electron microscope, information about the morphology, size, and structure of nanomaterials can be obtained.
Atomic Force Microscope (AFM)
Atomic Force Microscope (AFM) is a high-resolution microscope that measures changes in the Martini curvature of a sample surface by scanning the sample surface. The AFM can be used to measure a variety of samples, including solid, liquid, and gaseous materials, and can provide detailed information about the surface morphology and roughness of nanomaterials.
X-Ray Diffraction (XRD)
X-Ray Diffraction (XRD) is a technique used to study the crystal structure of materials. Through the detection and recording of X-rays, we can obtain information about the crystal structure of materials, and thus understand the crystal structure and crystal size of nanomaterials. XRD is widely used in the study of the structure and properties of nanomaterials.
UV-Vis Absorption Spectroscopy
UV-Vis absorption spectroscopy is a commonly used tool for analyzing the visible chemical properties of nanomaterials. It determines the absorption intensity of a sample solution to visible and ultraviolet light, obtaining the absorption spectrum of the sample. By analyzing the position and relative intensity of the absorption peaks, information about the wavelength of light absorbed, concentration, and particle size of nanomaterials can be obtained.
Industry articles
Safety Assessment of Nanoparticles in Food
Wang, Mengjie, et al. Nano Today 39 (2021): 101169.
Nanoparticles (NPs) have had a groundbreaking impact on human life, and due to their unique properties, they have been widely applied in many fields, including electronics, optics, chemistry, food, biology, and medicine. In the food industry, nanotechnology has been used in the production, processing, storage, and distribution of food, and nano-sensors have been used to detect pathogens or contaminants in food, thereby improving food safety. NPs in food include those used in food processing, food packaging, and food additives, and are used for purposes such as antimicrobial activity, color improvement, and increasing process stability.
Intentionally added NPs in ingested foods and NPs that migrate from packaging are important sources of human exposure to NPs. Some researchers have found that ingestion of NPs may cause biological effects such as DNA damage, protein denaturation, and the induction of oxidative stress, which highlights the importance of attention to the use of NPs in food. Some countries and international organizations have proposed regulatory requirements for NPs in food.
Predicting Potential Toxicity of Carbon Nanomaterials
Esimbekova, Elena N., et al. Toxicology in Vitro 45 (2017): 128-133.
Multiple studies have demonstrated that carbon nanotubes (CNTs) exhibit cytotoxicity and genotoxicity. Additionally, CNTs can amplify the toxicity of other pollutants. Assessing the toxicity of commercial CNT formulations is crucial, as they may have negative impacts on biological entities during manufacturing and use.
A bioluminescence enzyme inhibition assay was used to predict the potential toxicity of carbon nanomaterials (CNMs), including single-walled and multi-walled carbon nanotubes (SWCNTs and MWCNTs) as well as aqueous fullerene C60 (C60HyFn) solutions.
Guidance, standards and specifications related to nanomaterials
ISO
ASTM
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