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Most marketed pharmaceuticals consist of molecular crystals. The arrangement of the molecules in a crystal determines its physical properties and, in certain cases, its chemical properties, and so greatly influences the processing and formulation of solid pharmaceuticals, as well as key drug properties such as drugs solubility, stability, dissolution rate, bioavailability and tabletability, all of which makes the understanding of the crystalline state is crucial for many of the activities of the pharmaceutical industry. [1]
As a global leading pharmaceutical analysis services company, Alfa Chemistry provides crystallinity determination and other preformulation analysis services for minimizing the potential formulation and stability problems. Alfa Chemistry is the perfect partner for getting expertise, flexibility, and reliability with your pharmaceutical formulation projects.
Datta, S., & Grant, D. J. (2004). Crystal structures of drugs: advances in determination, prediction and engineering. Nature Reviews Drug Discovery, 3(1), 42.