Water Content Determination

In terms of pharmaceuticals, water affects the physical and chemical properties of a drug, including stability, effectiveness, and shelf life. Additionally, water acts as a carrier for drug ingredients and may affect the bioavailability of the product. Thus, water content determination holds high importance as it allows pharmaceutical professionals to understand the features and functionalities of a drug, providing useful insights into the quality control and continued development of pharmaceutical drugs. Alfa Chemistry provides water content determination. We fully understand the significance of water content in pharmaceuticals and the impact inaccurate water content can have on drug effectiveness and safety. Therefore, our services ensure the highest levels of precision and accuracy, backed by our team of skilled professionals and state-of-the-art technology.

Water sources in drug dosage forms

In pharmaceutical products, water can come from multiple sources. It can be added intentionally during the manufacturing process as a solvent or as an ingredient in the finished product. It also can be a component of the raw materials used. Furthermore, water can enter a product unintentionally from the environment during or after the manufacturing process due to insufficient packaging or storage conditions.
Regardless, a precise and specific examination of water content is needed for proper administration, handling, and storage of pharmaceutical drugs.

Alfa Chemistry's methods for water content determination include:

Noteworthy, among several methods, Karl Fischer titration is a popular and highly effective technique used for water content determination due to its effectiveness, accuracy, and ease of execution. Alfa Chemistry has many years of experience in developing and executing water determination by Karl Fischer methods and have successfully executed several projects. Our Karl Fischer methods include:

We are proud that Our Karl Fischer titration offers specificity and accurately determines water content even in low levels. It ascertains data on the water content regardless of whether the water is bound, free, or emulsified, thereby giving a complete analysis.