LTQ XL™ Linear Ion Trap Mass Spectrometer

With unmatched sensitivity and ultra-fast cycle times, the LTQ XL guarantees maximum mass spectral information with the fewest samples in the shortest amount of time. The combination of high quality spectra and advanced data analysis software packages from LTQ XL provides a complete solution for complex structural validation studies. LTQ XL extends the functionality and performance of ion trap mass spectrometry.

New Features Including:

• The upgradeable electron transfer cleavage (ETD) module can provide post-translational modification information for proteins not available with traditional lysis methods.

• Pulse Collision Energy Induced Dissociation (PQD) can provide low mass end fragment ion information.

• High selection of MS/MS analysis can give the spectra a better match in database and library search, improving the reliability of structural validation. In addition, rapid polarity switching and parental ion-related MS3 data correlation scanning can intelligently and quickly analyze the post-translational modification and identification of metabolite composition, and can be combined with high-end cyclotron resonance mass spectrometry to form the most advanced multi-level high-resolution hybridization mass spectrometer.

• The LTQ XL uses the latest Xcalibur operating platform and works with professional applications such as Mass Frontier, MetWorks and BioWorks. It is the best option in cutting-edge areas such as proteomics research, metabolite structure identification, quantitative drug screening, forensic and clinical testing.

Application Areas:

• Quantitative analysis of protein identification and differential expression

• Biomarker analysis

• Post-translational modification (PTM) study

• Metabolite identification and quantification Mass Frontier

• Fast LC method

Features & Benefits

• Unparalleled sensitivity and unmatched MSn spectral quality.

• Pulsed Q Dissociation (PQD) for generating more fragments and extending the low mass range.

• Electron Transfer Dissociation (ETD) option provides sequence information not available from conventional methods.

• High Resolution Isolation (HRI) enables isolation of isobaric masspeaks for cleaner MS spectra.

• Ultra-fast polarity switching for high sensitivity analysis of unknowns.

• Automated Data Dependent neutral loss for PTM and biotransformation analyses.

Figure 1. The LTQ XL