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Note: this service is for Research Use Only and Not intended for clinical use.
Fig 1 The structure of ligand bound ErbB11.Biological agents or biotechnology drugs include polypeptides, recombinant proteins, monoclonal antibodies, oligonucleotides and so on. Ligand binding analysis (LBA) is a major method for quantifying biomarkers, biomarkers and anti-drug antibody to support the development of biotherapy. LBA is widely used in pre-clinical and clinical development for the quantitation of proteins, antibodies and other large molecules in pharmacokinetic, toxicological, pharmacodynamic and immunogenic studies. LBA has many analytical challenges, such as high analytical variability, non-linear correction, narrow dynamic range, large matrix interference and so on. In the process of analysis, the changes of reagents, instruments and laboratory environment may affect the analytical performance. Therefore, it is difficult to determine the selectivity, specificity and quantitative range of the method.
Alfa Chemistry's scientists have extensive experience in biopharmaceutical analysis, and combined with our state-of-the-art analytical technology platform, we can provide accurate and repeatable experimental results to clients around the world. Our experts will communicate with you to select the most appropriate ligand binding analysis solution and verify it to ensure reliable data. And we will develop strategic methods to ensure the selectivity, specificity and quantitative scope of the analysis, to minimize matrix interference, and to support compliance with global regulatory standards. Alfa Chemistry is your reliable partner for ligand binding analysis, please feel free to contact us for more information on LBA .
Alfa Chemistry's ligand binding assay methods include but not limited to: