PFAS Testing for Biological Tissues and Fluids

Per- and polyfluoroalkyl substances (PFAS) represent a group of synthetic chemicals widely used in industrial and consumer products. However, their environmental persistence and bioaccumulative nature have raised significant concerns regarding human exposure and associated health risks (as shown in Fig. 1). PFAS can accumulate in biological tissues and fluids such as blood, serum, liver, kidney, breast milk, and urine, making biological monitoring essential for exposure assessment and health risk evaluation. Alfa Chemistry provides advanced PFAS testing services for biological tissues and fluids, supporting research institutions, regulatory bodies, healthcare organizations, and industries in achieving precise exposure assessments.

Fig.`1. Health effects associated with PFAS exposure.

Why PFAS testing in biological tissues and fluids is critical

• Human Health Risk Assessment: PFAS exposure has been linked to adverse health effects, including developmental issues, immune dysfunction, endocrine disruption, and certain cancers. PFAS testing provides direct evidence of internal exposure levels.
• Epidemiological Studies: Biological PFAS data is crucial for correlating exposure with health outcomes in populations.
• Regulatory Compliance: Authorities in the EU, US, and other regions increasingly require biological monitoring in occupational settings or contaminated communities.
• Effectiveness of Intervention Measures: PFAS testing helps evaluate the success of exposure mitigation strategies, such as the provision of clean drinking water or dietary modifications.

Biological tissues and fluids we can test

Our laboratory is equipped to handle a wide range of biological matrices (including human samples and animal samples) for PFAS analysis, including but not limited to:

• blood (whole blood, plasma, and serum)
• Urine
• Breast milk
• Liver, kidney, and adipose tissue
• Saliva and other secretions
• Hair and nails (as auxiliary indicators)

We accept samples for routine screening, research studies, and legal or regulatory investigations. All analyses are performed under strict chain-of-custody and quality assurance protocols.

Our PFAS testing capabilities include:

Targeted Analysis of Regulated and Emerging PFAS

Ultra-trace Quantification

Method Validation and Standardization

Custom PFAS Panels

Our PFAS testing supports a wide range of applications:

• Occupational health surveillance in industries where PFAS exposure is possible (e.g., firefighting, chemical manufacturing).
• Community exposure studies for populations near contaminated sites.
• Human biomonitoring programs run by governmental or academic bodies.
• Toxicological research into PFAS bioaccumulation and health outcomes.
• Clinical studies investigating correlations between PFAS levels and diseases.
• Legal and regulatory support in environmental health lawsuits or compliance verification.

Our advantages:

• Accredited testing facility with a proven track record in ultra-trace analysis of PFAS.
• Cutting-edge instrumentation enabling high sensitivity, specificity, and throughput.
• Experienced technical team with deep expertise in PFAS analysis and biological sample handling.
• Flexible services including standard testing, method development, and customized study support.
• Global service reach with sample logistics support and multilingual reporting.

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