Thermal Analysis

The International Confederation for Thermal Analysis and Calorimetry (ICTAC) defines "thermal analysis" as a group of techniques in which a physical or chemical property of a sample is monitored against time or temperature while the temperature of the sample, in a specified atmosphere, is programmed. Thermogravimetry (TG) is a technique in which sample weight is measured as a function of temperature. The sample is loaded on a high precision thermobalance within the furnace and weighed continuously during the course of the heating program. The mass loss associated with a thermal reaction is measured between the inflection points of the TG curve. Alfa Chemistry provides thermal analyses services to a variety of industry covering plastics, rubber, coatings, pharmaceuticals, catalysts, inorganic materials, metal materials, composite materials, chemical and chemical fields, metallurgical fields, geological fields, physical fields and ceramic fields, as well as aerospace fields. Our scientists have years of experiences in identification analysis of inorganic, organic, pharmaceutical and polymer substances and phase map research services. We can help you implement comprehensive thermal analysis including thermal stability test, antioxidant test, solid-gas reaction research, catalytic performance determination, reaction dynamics research, reaction thermal determination, phase transition and crystallization process research services. Our staff of specialists can handle your products under differential thermal analysis (DTA), differential scanning alorimetry (DSC), thermogravimetry analysis (TG), dynamic mechanical analysis (DMA), thermodilatometry (TD), dielectric thermal analysis (DEA), thermally stimulated current (TSC), evolved gas analysis (EGA), and emanation thermal analysis (ETA). It is no exaggeration to say, Alfa Chemistry will be your one-stop shop for all your thermal analysis test and research.

Our testing services categories include the following:

Thermal Analysis of Drugs

Thermal analysis is among the most widely used techniques for analyzing substances of pharmaceutical interest and resolving and identifying problems in the field of pharmaceutical technology. Thermal analysis techniques such as thermogravimetric analysis (TGA), differential thermal analysis (DTA), and differential scanning calorimetry (DSC) are the accepted methods of drug characterization. They are used to assess the purity of pharmaceutical substances, polymorphism, stability, compatibility, decomposition kinetics, phase transition and solvation, as well as hydration. The flow chart shows the procedure used for evaluating the thermal stability of drug. First, measurements of differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) were performed to characterize the prototype, later for analysis of drug-excipient interaction.

Fig.1 Flowchart for evaluating the thermal stability of drug

Our Thermal Analysis of Drugs includes:

Scientists at Alfa Chemistry are adept at the latest thermal analytical methods of drug. We have the advanced analytical instruments and top experts in all analytical areas. We can provide rapid, reliable, safe and clean method in thermal analysis areas. We guarantee high quality standards and we work closely with our customers. Glad to hear your comments and look forward to cooperating with you.