CAS 364732-88-7 (R)-Phanephos - Catalysts / Alfa Chemistry

Synonyms

(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane

Molecular Weight

576.65

Molecular Formula

C40H34P2

InChI

1S/C40H34P2/c1-5-13-35(14-6-1)41(36-15-7-2-8-16-36)39-29-31-21-25-33(39)27-23-32-22-26-34(28-24-31)40(30-32)42(37-17-9-3-10-18-37)38-19-11-4-12-20-38/h1-22,25-26,29-30H,23-24,27-28H2

InChI Key

GYZZZILPVUYAFJ-UHFFFAOYSA-N

Melting Point

222-226 °C

Assay

0.96

Optical Activity

[α]/D -34±4°, c = 1 in chloroform

MSDS

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COA

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Spec Sheet

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Application

Efficient ligand for asymmetric hydrogentation of dehydroamino acids, methyl esters and keytones.
(R)-(-)-4,12-Bis(diphenylphosphino)-[2.2]-paracyclophane may be used as a ligand in the following processes:
Enantioselective reductive cyclization of 1,6-enynes via asymmetric hydrogenation in the presence of a rhodium catalyst to form alkylidene-substituted heterocycles.
Asymmetric hydroboration of 3,3-disubstituted cyclopropenes to form 2,2-disubstituted cyclopropyl boronates.
Asymmetric ring-opening reactions of azabenzonorbornadienes in the presence of zinc(II) triflate and palladium(II) acetate to form aminodihydronaphthalenes.