CAS 373-57-9 Boron trifluoride-methanol solution

Synonyms

CH4BF3O; B0894; Boron trifluoride - methanol reagent (10-20%) [for esterification] (1ml*10); Boron trifluoride solution; AKOS030228421; RTR-033660; .BF3 in Methanol; Boron trifluoride-methanol in methanol; BF3 methanol; Boron trifluoride methanol complex solution, 13-15% BF3 basis;

IUPAC Name

methanol;trifluoroborane;

Molecular Weight

99.847g/mol

Molecular Formula

CH4BF3O;

Canonical SMILES

B(F)(F)F.CO;

InChI

InChI=1S/CH4O.BF3/c1-2;2-1(3)4/h2H,1H3;;

InChI Key

JBXYCUKPDAAYAS-UHFFFAOYSA-N;

Storage

2-8°C

Complexity

Covalently-Bonded Unit Count

EC Number

220-543-9

Exact Mass

100.031g/mol

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

Monoisotopic Mass

100.031g/mol

Topological Polar Surface Area

20.2A^2

Application

Boron trifluoride-methanol solution is a versatile reagent that serves multiple purposes in chemical analysis and synthesis. As a colorless to amber solution, it is utilized primarily as an esterification reagent and a powerful acidic catalyst, particularly effective in the esterification of fatty acids. This capability is expanded through its application in transmethylation processes, such as in the GC analysis of ritalinic acid and the treatment of lipids for determining fatty acid methyl esters and dimethylacetals. Additionally, the solution functions as an alternative to certain acids in the synthesis of purine-rich oligomers and is employed as a Lewis acid in the preparation of geminal bis-peroxides from ketals and enol ethers with t-butyl hydroperoxide. Boron trifluoride-methanol also facilitates the mild deacetylation of amines and is instrumental in catalyzing the transesterification of vegetable oils to produce biodiesel.

February 12, 2025

An Essential Catalyst for Esterification and Analysis

I used Alfa Chemistry's Boron trifluoride-methanol solution in our research to catalyze fatty acid methyl esterification efficiently. This reagent simplified the GC analysis of ritalinic acid and facilitated biodiesel transesterification. Highly recommended for its effectiveness.