Bis(η 3 -allyl)di( µ -chloro)dipalladium(II)

Application

Bis(η³-allyl)di(μ-chloro)dipalladium(II) serves a crucial role in organic synthesis as a versatile catalyst. This compound is instrumental in various chemical reactions and processes including the Heck reaction where it acts as a key catalyst. It also facilitates the preparation of complex structures such as cyclopentadienyl allyl palladium through its reaction with cyclopentadienyl anion. As a precatalyst, it is indispensable for asymmetric and cross-coupling reactions, contributing to the synthesis of 1,4-diallyl-1,2-dihydroisoquinolines and engaging in greener Buchwald-Hartwig coupling reactions. Furthermore, it aids in crafting cationic palladium catalysts and the formation of heterocyclic carbene-palladium-eta³-allyl chloride complexes, which are essential for Suzuki-Miyaura cross-coupling reactions. The compound's utility extends to being a catalyst in the silylation of organobromides, the synthesis of α-aryl carbonyl compounds from aldehyde and aryl halide coupling reactions, and the production of arylthiophene derivatives via C-H functionalization. Proving itself as an enantioselective hydrosilylation precatalyst for olefins and participating in nucleophilic allylation-alkoxyallylation reactions, it is also employed for asymmetric allylic alkylation and amination. As a palladium source, it's essential for cross-coupling reactions and can be coupled with Trost ligands, enhancing its versatility in chemical synthesis, including the carbostannylation of alkynes and arylation of aldehydes.