CAS 2926-30-9 Sodium Triflate - Catalysts / Alfa Chemistry

Synonyms

2926-30-9; Sodium trifluoromethanesulfonate, 98%; CHEMBL3326865; PC6572; SCHEMBL158641; sodium trifluoro methane sulfonate; DTXSID20635510; M921; MFCD00061607 (98%); ZX-AP001846;

IUPAC Name

sodium;trifluoromethanesulfonate;

Molecular Weight

172.053g/mol

Molecular Formula

CF3NaO3S;

Canonical SMILES

C(F)(F)(F)S(=O)(=O)[O-].[Na+];

InChI

InChI=1S/CHF3O3S.Na/c2-1(3,4)8(5,6)7;/h(H,5,6,7);/q;+1/p-1;

InChI Key

XGPOMXSYOKFBHS-UHFFFAOYSA-M;

Complexity

163

Covalently-Bonded Unit Count

Exact Mass

171.942g/mol

H-Bond Acceptor

Heavy Atom Count

Monoisotopic Mass

171.942g/mol

Topological Polar Surface Area

65.6A^2

Application

Sodium triflate, or Sodium trifluoromethanesulfonate, is a versatile and efficient substance renowned for its utility in various scientific and industrial applications. As a water-soluble, anionic compound that is colorless, odorless, and non-toxic, it holds significant value as both a reagent and catalyst in organic synthesis and industrial processes. Sodium triflate is particularly recognized for its strong acidity, making it an effective catalyst in reactions such as the catalytic asymmetric Mannich-type, Diels-Alder, and those occurring in aqueous environments. Additionally, it serves as a reliable chaotropic mobile phase additive in reversed-phase liquid chromatography, and finds use in preparing ionic liquids, as well as N-fluoro-2-methylpyridinium triflate via reaction with dinitrogen difluoride. Moreover, it acts as a supporting electrolyte in electrochemical O-glycosylation of primary alcohols with O-protected thioglycosides, and enables the synthesis of aryl fluorides through silver-catalyzed fluorination of arylstannanes. Its multifunctional nature and reactivity make Sodium triflate an indispensable component in advancing chemical research and industrial chemistry.

January 18, 2025

Reliable Catalyst for Research Success

Sodium Triflate has been instrumental in my research. As a catalyst, it enhanced our Mannich-type reactions and aided in RP-LC as a chaotropic additive. Its versatility in synthesis is truly commendable.