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Sodium Acetate Trihydrate

Catalog Number
ACM6131904-2
Product Name
Sodium Acetate Trihydrate
CAS
6131-90-4
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IUPAC Name
sodium; acetate; trihydrate
Molecular Weight
136.08
Molecular Formula
C2H9NaO5
Canonical SMILES
[Na+].[O-]C(=O)C.O.O.O
InChI
InChI=1S/C2H4O2.Na.3H₂O/c1-2(3)4;;;;/h1H3,(H,3,4);;3*1H2/q;+1;;;/p-1
InChI Key
AYRVGWHSXIMRAB-UHFFFAOYSA-M
Melting Point
58°C
Flash Point
40°C
Density
1.45 g/cm³
Appearance
White to colourless crystals or powder
Assay
0.99
Complexity
34.6
Covalently-Bonded Unit Count
5
EC Number
204-823-8
Exact Mass
136.0347
Formal Charge
0
H-Bond Acceptor
5
H-Bond Donor
3
Heavy Atom Count
8
MDL Number
MFCD00071557
MeSH Entry Terms
Sodium Acetate;Sodium Acetate Trihydrate;Sodium Acetate, Anhydrous
Monoisotopic Mass
136.0347
Physical State
White powder
Rotatable Bond Count
0
Stability
Stable. Incompatible with strong oxidizing agents, halogens.
UNII
4550K0SC9B
Application
Sodium acetate trihydrate serves a multifaceted role across various industries due to its versatile chemical properties. As the trihydrate sodium salt of acetic acid, it manifests as colorless, odorless crystals that weather in air and are soluble in water and ether, with a pH of 8.9 in a 0.1M aqueous solution. It functions as a buffering agent, particularly useful in maintaining a pH range of 4.0 to 6.0. This makes it invaluable in biological applications such as the purification and precipitation of nucleic acids and in protein crystallization. Additionally, it acts as a mordant in dyeing, a pickling agent in chrome tanning, and a neutralizer for sulfuric acid in waste streams. In the textile and synthetic rubber industries, sodium acetate trihydrate helps retard the vulcanization of chloroprene. It is pivotal in creating esters from alkyl halides and finds use in photography, food preservation, glucose purification, meat preservation, tanning, and as a dehydrating agent. Its role in analytical chemistry as a component in buffer solutions enhances its utility. The compound transitions to an anhydrous form upon heating above 120°C, revealing its adaptable nature. Its integration into buffers within pharmaceuticals, such as intramuscular and intravenous formulations, underlines its functionality in reducing bitterness and enhancing antimicrobial properties, effectively inhibiting certain bacterial growth. Furthermore, sodium acetate is employed in food preservation and therapeutically in treating metabolic acidosis in premature infants, as well as in hemodialysis solutions, exemplifying its broad spectrum of applications.
December 30, 2024

Essential for Nucleic Acid Research

Using Alfa Chemistry's Sodium Acetate Trihydrate significantly improved our nucleic acid purification process. Its reliable buffering capacity and solubility enhance precision in experiments, ensuring consistent and reproducible results in protein crystallization and DNA precipitation.

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