CAS 69098-15-3 Nickel(II) Chloride Hydrate - Catalysts / Alfa Chemistry

Synonyms

Nickel(II) chloride

IUPAC Name

Dichloronickel;hydrate

Molecular Weight

147.61

Molecular Formula

Cl2H2NiO

Canonical SMILES

O.Cl[Ni]Cl

InChI

InChI=1S/2ClH.Ni.H₂O/h2*1H;1H2/q;+2;/p-2

InChI Key

HGGYAQHDNDUIIQ-UHFFFAOYSA-L

Melting Point

1001 °C

Purity

99%+

Solubility

Freely soluble in water

Appearance

Green crystalline aggregates

Complexity

2.8

Covalently-Bonded Unit Count

EC Number

231-743-0

Exact Mass

145.883612

Formal Charge

H-Bond Acceptor

H-Bond Donor

Heavy Atom Count

MDL Number

MFCD00149808

MeSH Entry Terms

nickel chloride;nickel chloride dihydrate;nickel chloride hemihydrate;nickel chloride heptahydrate;nickel chloride hexahydrate;nickel chloride hydrate;nickel chloride monohydrate;nickel chloride monohydroxide;nickel chloride tetrahydrate;nickel chloride trihydroxide

Monoisotopic Mass

145.883612

Physical State

Green crystals

Rotatable Bond Count

Topological Polar Surface Area

1 Å²

Application

Nickel(II) Chloride Hydrate serves multiple purposes across various chemical processes, primarily functioning as a catalyst and a precursor in organic chemistry. It plays a vital role in electroplating and is utilized as a catalyst in organic conversions, such as the chemo-selective thioacetalization of aldehydes. When combined with lithium aluminum hydride, it acts as an effective reducing agent for alkenes, alkynes, and organic halides, while also having the capability to cleave N-O bonds and open epoxides. This compound is a key precursor to various nickel-phosphine complexes like bis(triphenylphosphine)nickel(II) chloride, which are instrumental in reactions such as alkyne trimerizations, carbonylations, and Suzuki-Miyaura cross-coupling reactions, offering an alternative to palladium(0) catalysts. Additionally, it provides the foundation for the acetylacetonate complex of nickel, essential for producing the 1,5-cyclooctadiene complex, a significant reagent in organonickel chemistry. Furthermore, Nickel(II) Chloride Hydrate is crucial for preparing the sandwich compound nickelocene through the dimethoxyethane complex of nickel chloride.

February 14, 2025

Essential Catalyst for Advanced Organic Conversions

Nickel(II) Chloride Hydrate from Alfa Chemistry is indispensable in my lab work. It's effective for electroplating and vital as a catalyst in chemo-selective thioacetalization processes. It enhances our organic synthesis efficiencies significantly.