Description
Levamisole ((-)-Tetramisole) hydrochloride is an anthelmintic and immunomodulator belonging to a class of synthetic imidazothiazole derivatives. Levamisole hydrochloride has antiviral effects against HSV.
Synonyms
Meglum; Levamisole HCl(Ergamisol); Imidazo[2, 2,3,5,6-tetrahydro-6-phenyl-, monohydrochloride, L-(-)-; R-12564; Levamisole hydrochloride; 74191-78-9; 16595-80-5; FT-0625516; SMR001230807; Levamisole hydrochloride [USAN:USP];
IUPAC Name
(6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride;
Molecular Weight
240.749g/mol
Molecular Formula
C11H13ClN2S;
Canonical SMILES
C1CSC2=NC(CN21)C3=CC=CC=C3.Cl;
InChI
InChI=1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1;
InChI Key
LAZPBGZRMVRFKY-HNCPQSOCSA-N;
Purity
99.86%
Solubility
Water 210 (mg/mL);Methanol sol. (mg/mL);Propylene glycol sol. (mg/mL);Ethanol sl. sol. (mg/mL);>36.1 [ug/mL];
Storage
0-6°C
Complexity
246
Covalently-Bonded Unit Count
2
Defined Atom Stereocenter Count
1
EC Number
240-654-6
Exact Mass
240.049g/mol
H-Bond Acceptor
2
H-Bond Donor
1
Heavy Atom Count
15
Monoisotopic Mass
240.049g/mol
NSC Number
177023
Rotatable Bond Count
1
Stability
Bulk: Levamisole appears to be stable in the bulk form at 60°C for at least four weeks.
Solution: At 100 mg/mL concentrations in water and pH 7 buffer, the compound is stable for at least 9 days when stored at ambient temperature under normal laboratory illumination.;
Solution: At 100 mg/mL concentrations in water and pH 7 buffer, the compound is stable for at least 9 days when stored at ambient temperature under normal laboratory illumination.;
Topological Polar Surface Area
40.9A^2
UNII
DL9055K809
