Bis(1,5-cyclooctadiene)diiridium(I) Dichloride

Application

Bis(1,5-cyclooctadiene)diiridium(I) dichloride serves a pivotal role in the realm of homogeneous catalysis, functioning as an essential precursor to a host of iridium complexes. These complexes are instrumental in a variety of catalytic reactions, such as carbonylation, hydrosilylation, hydroformylation, asymmetric allylic substitutions, metathesis, and chiral catalysis. This compound is notably utilized in creating Crabtree's catalyst, which is crucial for hydrogenation and hydrogen-transfer processes. Additionally, it contributes to the development of catalysts for the asymmetric hydrogenation of tri- and tetrasubstituted olefins, the enantioselective reduction of imines, allylic alkylation, and allylic amination and etherification. Furthermore, it facilitates the reaction of aroyl chlorides with internal alkynes to yield substituted naphthalenes and anthracenes, and supports the Ir-catalyzed addition of acid chlorides to terminal alkynes. The compound also enables intramolecular hydroamination of unactivated alkenes with secondary alkyl- and arylamines, enantioselective [2+2] cycloaddition, silyl-directed ortho-borylation of arenes, Ir-catalyzed cross-coupling of styrene derivatives with allylic carbonates, and transfer hydrogenative C-C coupling, underscoring its versatility and importance in modern chemical synthesis.