CAS 1067883-58-2 2-[2-(Dicyclohexylphosphino)phenyl]-N-methylindole

Synonyms

2-[2-(Dicyclohexylphosphino)phenyl]-1-methyl-1H-indole; CM-Phos

IUPAC Name

dicyclohexyl-[2-(1-methylindol-2-yl)phenyl]phosphane

Molecular Weight

403.54

Molecular Formula

C27H34NP

InChI

PFJAHDIIEPTASS-UHFFFAOYSA-N

InChI Key

InChI=1S/C27H34NP/c1-28-25-18-10-8-12-21(25)20-26(28)24-17-9-11-19-27(24)29(22-13-4-2-5-14-22)23-15-6-3-7-16-23/h8-12,17-20,22-23H,2-7,13-16H2,1H3

Boiling Point

582.4±33.0 °C(Predicted)

Melting Point

180-185 °C

Purity

97%

Appearance

Solid

Complexity

491

Covalently-Bonded Unit Count

Exact Mass

403.243g/mol

Heavy Atom Count

Isomeric SMILES

CN1C2=CC=CC=C2C=C1C3=CC=CC=C3P(C4CCCCC4)C5CCCCC5

Monoisotopic Mass

403.243g/mol

Rotatable Bond Count

Topological Polar Surface Area

4.9A^2

MSDS

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COA

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Spec Sheet

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Application

Suzuki-Miyaura Coupling of Aryl Mesylates and alkenyl tosylate and mesylate bearing alkyl, methoxy, aldehyde, keto, nitrile, ester, and heteroaryl substitution.

Sonogashira Coupling of Aryl Mesylates, R' = alkyl, aryl; R = C(O)R, COOMe, CHO, CN.

Buchwald-Hartwig Amination of Aryl Mesylates, R = cyano, chloro, methoxy, keto, ester and etc.

Additional catalyzed reactions include Cyanation of functional Aryl Mesylates and Chlorides; Hiyama Coupling of Aryl Mesylates; Direct Arylation of Heterocycles with Aryl Mesylates; Borylation of Aryl Mesylates.