Molecular Weight
230.09
Molecular Formula
C12H14FeO
Purity
>95.0%(T)
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1-Hydroxyethylferrocene
Catalog Number
ACM1277492-2
Product Name
1-Hydroxyethylferrocene
Structure
![{[CurrentData.Name]}](https://resource.alfachemic.com/structure/1277-49-2.gif)
CAS
1277-49-2
Application
1-Hydroxyethylferrocene is a versatile yellow to yellow-orange crystalline powder that serves several important roles in chemical reactions. It functions as a ligand in titanium-catalyzed intermolecular hydroamination of terminal alkynes, facilitating both Markovnikov and anti-Markovnikov additions, which are crucial in synthetic chemistry. Additionally, it acts as a reactant in single-electron transfer living radical polymerization reactions, contributing to the creation of advanced polymer structures. This compound is also instrumental in the preparation of ferrocene-modified thiopyrimidines, which are explored for their potential use as anticancer agents. Furthermore, 1-Hydroxyethylferrocene is utilized in the preparation of reversible addition-fragmentation chain transfer (RAFT) agents, playing a key role in RAFT polymerization of styrene, allowing for controlled polymerization processes vital for producing various polymer-based materials.
February 27, 2025
Exceptional Versatility in Research Applications
1-Hydroxyethylferrocene from Alfa Chemistry is a game-changer. I used it in radical polymerization and titanium-catalyzed hydroamination, yielding excellent results with minimal effort. Its versatility and consistency are unmatched in my research work.
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