Long Peptide Synthesis

As a key class of bioactive molecules, long peptides are commonly used in drug development, vaccine design and biomedical research. The synthesis of long peptides involves the sequential addition of amino acids to create the desired sequence. Different techniques, such as solid phase peptide synthesis or liquid phase peptide synthesis, can be utilized to efficiently assemble long peptide chains. The process requires precise control over the reaction conditions, protecting groups, and purification steps to ensure the correct sequence and high purity of the final product. After long-term exploration and accumulation, Alfa Chemistry has continuously optimized the synthesis process and methods, and solved the problem of difficulty in synthesizing long peptides. Our long peptides have a high synthesis success rate and stable quality.

What We Offer

Our long peptide synthesis services are designed to deliver high-quality, cost-effective, and tailored solutions to meet the diverse research and development needs of our clients in the biotech, pharmaceutical, and academic sectors. The long peptide synthesis services we provide include but are not limited to the following:

• Design and synthesis of long peptides
• Scale-up production of long peptides
• Quality assessment of long peptides

Synthesis Technologies

Microwave synthesis. Microwave synthesis is a method that uses microwave radiation to accelerate chemical reactions. Microwave radiation can convert electromagnetic radiation inside molecules into thermal energy inside molecules, thereby increasing the reaction rate. Under microwave radiation, the vibration and rotation rates of molecules increase, making chemical reactions occur faster. For some amino acids that are difficult to condense during the synthesis process, we use the microwave method for synthesis. This method has significant effects, greatly shortens the reaction time, and reduces the production of by-products.

Fragment synthesis. When certain peptides are difficult to synthesize by conventional synthesis methods and difficult to purify, we can use fragment synthesis. That is, certain amino acids in a certain section of the peptide are condensed, and then condense them as a whole into the peptide chain. This method can also solve many problems in synthesis.

Hydrazide synthesis. The hydrazide synthesis method is widely applicable to the synthesis of long peptides containing Cysteine (Cys). This method divides the entire peptide chain into multiple sequences and synthesizes them separately based on the position of Cys in the peptide chain, and finally obtains the target peptide through liquid phase condensation. The hydrazide synthesis method not only greatly shortens the synthesis time of long peptides, but also significantly improves the purity of the final product.

Our Advantages

• Guaranteeing sufficient delivery. Alfa Chemistry ensure that each long peptide synthesized is delivered in sufficient quantity to avoid the risk of insufficient quantity.
• Strict quality system. Alfa Chemistry has a comprehensive quality control management platform. We can provide you with chromatograms and mass spectrum reports, and can also provide special services according to your needs.
• Stable product quality. Alfa Chemistry has a fully automated production platform to ensure the batch-to-batch stability of long peptides and always provide high-quality long peptide products, from mg level to kilogram level.
• Efficient service. Alfa Chemistry provide one-on-one project services and communicate with you regularly about project progress through meetings. In addition, our team of experts will provide consultation and support throughout the synthesis of your long peptides.
• Fast delivery cycle. Delivery takes 2-3 weeks, shortening your waiting time.
• Reasonable price system. Alfa Chemistry provide the most competitive prices based on your product requirements and order quantity.
• Strict confidentiality. Once cooperation is reached, Alfa Chemistry will sign a confidentiality agreement with you.

Service Process