Cyclic Peptide Synthesis

Cyclic peptides are a type of peptide molecules with a cyclic structure. Unlike linear peptides with straight chain structures, cyclic peptides do not have free N-terminal and C-terminal, thereby improving stability and resistance to enzymatic degradation. Cyclic peptides have a wide range of biological and pharmacological activities. Therefore, the ability to synthesize cyclic peptides efficiently and accurately is critical to exploring their potential applications in drug discovery, molecular recognition, and biological research. Alfa Chemistry has mature cyclic peptide synthesis technology. We provide a series of cyclic peptide synthesis services to meet our customers' needs for different types of cyclization.

What We Offer

We provide a range of cyclic peptide synthesis services to meet the diverse needs of our customers. According to the type of ring formation, it can be generally divided into two categories, namely disulfide bond cyclic peptide synthesis services and amide bond cyclic peptide synthesis services.

Disulfide bond cyclic peptide synthesis

Depending on the number of disulfide bonds, we can provide the following cyclic peptide synthesis services.

Synthesis of single disulfide bond cyclic peptides
Synthesis of cyclic peptides formed by two pairs of disulfide bonds
Synthesis of cyclic peptides formed by three pairs of disulfide bonds

Depending on whether the ring formation is inside or outside the molecule, we can provide the following cyclic peptide synthesis services.

Synthesis of cyclic peptides formed by intramolecular disulfide bonds
Synthesis of cyclic peptides formed by intermolecular disulfide bonds

Amide bond cyclic peptide synthesis

Peptide head-to-tail cyclization. In the peptide sequence, the N-terminal amino group and the C-terminal carboxyl group form an amide bond to form a ring.
Peptide side chain cyclization. The amino and carboxyl groups on the side chain groups in the peptide sequence form amide bonds to form rings.

In addition, we also provide synthesis services for bicyclic peptides and lactone cyclic peptides. It is worth mentioning that due to the huge potential of RGD (Arg-Gly-Asp) cyclic peptides in tumor treatment, we also provide the following RGD cyclic peptide synthesis services, including:

Synthesis of cyclic peptides containing RGD sequences formed by disulfide bonds
Synthesis of cyclic peptides containing RGD sequences formed by amide bonds

Our Advantages

Guaranteeing sufficient delivery. Alfa Chemistry ensure that each cyclic peptide synthesized is delivered in sufficient quantity to avoid the risk of insufficient quantity.
Strict quality system. Alfa Chemistry has a comprehensive quality control management platform. We can provide you with chromatograms and mass spectrum reports, and can also provide special services according to your needs.
Stable product quality. Alfa Chemistry has a fully automated production platform to ensure the batch-to-batch stability of cyclic peptides and always provide high-quality cyclic peptide products, from mg level to kilogram level.
Efficient service. Alfa Chemistry provide one-on-one project services and communicate with you regularly about project progress through meetings. In addition, our team of experts will provide consultation and support throughout the synthesis of your cyclic peptides.
Fast delivery cycle. Delivery takes 2-3 weeks, shortening your waiting time.
Reasonable price system. Alfa Chemistry provide the most competitive prices based on your product requirements and order quantity.
Strict confidentiality. Once cooperation is reached, Alfa Chemistry will sign a confidentiality agreement with you.

Cyclic Peptide Synthesis

What We Offer

Disulfide bond cyclic peptide synthesis

Amide bond cyclic peptide synthesis

Our Advantages

Service Process