Osthole
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Osthole

Osthole

Product Name: Osthole
CAS No: 484-12-8
Catalog Number: ALPE-AM012
Specification: 98%
Analysis: HPLC
Formula: C15H16O3
Molecular Weight: 244.29
Appearance: White Fine Powder

Description

Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, is a bioactive simple coumarin derivative extracted from many medicinal plants. It is mainly distributed in 14 species of Umbelliferae and 17 species of Rutaceae. It has also been found in some species of Leguminosae and Compositae. The results of in vitro and in vivo experiments show that osthole has a variety of pharmacological effects, including anti-tumor, anti-inflammatory, neuroprotective, osteogenic, cardiovascular protective, antimicrobial and anti-parasitic. In addition, pharmacokinetic studies have shown that the uptake and utilization of osthole in the body is fast and effective.

Specification

ItemSpecification
Organoleptic
ColorWhite
OdorCharacteristic
AppearanceFine powder
Physical Characteristics
Particle Size100% pass 80 mesh
Loss on Drying≤5%
Total Ash≤5%
Solvents ResidueMeet Eur.Ph.7.0 <5.4>
Pesticides ResidueMeet USP Requirements
Heavy Metals
Total Heavy Metals≤10 ppm
Arsenic (As)≤1 ppm
Lead (Pb)≤2 ppm
Cadmium (Cd)≤1 ppm
Mercury (Hg)≤0.5 ppm
Microbiological Tests
Total Plate Count≤1000 CFU/g
Total Yeast & Mold≤100 CFU/g
E.coliNegative
SalmonellaNegative
StorageKeep in a cool & dry place. Stay away from moisture, light and oxygen.

Health Benefits

  • Supports Bone Health

Studies have shown that osthole can promote the proliferation and differentiation of osteoblasts, inhibit the formation and activity of osteoclasts, and thus facilitate bone remodeling and increase bone density [1]. This makes it a potential drug for the treatment of osteoporosis.

  • Promotes Cardiovascular Health

Osthole has been shown to have a protective effect on the heart and circulatory system. It may help lower blood pressure and improve blood vessel function, thereby reducing the risk of cardiovascular disease.

  • Anti-Tumor Effect

More and more evidence shows that osthole has the anti-tumor effect by inhibiting tumor cell growth and inducing apoptosis.

Choose Alfa Chemistry

Osthole is a promising natural compound. As a professional supplier of plant monomer, Alfa Chemistry is committed to providing customers with the most cost-effective osthole under the premise of quality assurance. We are equipped with a professional R&D team to continuously learn the latest product knowledge and technology. If you have any need, please feel free to contact us.

Reference

  1. Sun, M.; et al. Osthole: An overview of its sources, biological activities, and modification development. Medicinal Chemistry Research. 2021, 30(10): 1767-1794.

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