Coix Lacryma-Jobi-Derived Nanovesicles

Product Name: Coix Lacryma-Jobi-Derived Nanovesicles
Catalog Number: ALPE-PN004
Plant Source: Coix lacryma-jobi L.
Particle Size: 30–200 nm
Particle Concentration: ≥5 × 10¹⁰ particles/g

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Coix lacryma-jobi-derived nanovesicles represent a new frontier in botanical skincare, merging the time-honored benefits of Coix lacryma-jobi (Job's tears) with state-of-the-art nanotechnology. These naturally secreted, nano-sized vesicles are isolated through precision ultracentrifugation, forming phospholipid-based carriers that encapsulate a rich spectrum of bioactives—including omega-9 fatty acids, natural lipids, anti-inflammatory agents, and antimicrobial compounds.

Designed to penetrate the skin barrier efficiently, Coix lacryma-jobi-derived nanovesicles offer a multifunctional skincare approach: they help regulate sebum production, soothe sensitive and inflamed skin, and reinforce the skin's natural defense. Their gentle, biocompatible profile makes them ideal for acne-prone and reactive skin, while their enhanced stability and targeted delivery support long-lasting results.

• Sebum Control & Anti-Acne: Reduces excess oil secretion by modulating sebaceous gland activity and minimizing acne recurrence through antibacterial action.
• Barrier Repair & Soothing: Rich in omega-9 and natural lipids to reinforce skin barrier and calm irritation caused by inflammation (IL-6, TNF-α).
• Enhanced Penetration: Nano-sized vesicles with negative surface charge facilitate deep skin absorption via intercellular lipid pathways.
• Long-Term Stability: Double-layer lipid membrane protects bioactives from oxidation, enzymatic degradation, and environmental stress.
• Targeted Delivery: Surface proteins (e.g., CD63, adhesion molecules) recognize damaged skin cells and immune cells to boost collagen synthesis and anti-inflammatory signaling.

• Facilitates intracellular delivery by fusing with keratinocyte and fibroblast membranes
• Enhances bioavailability of traditionally low-permeability ingredients like polysaccharides and triterpenes
• Demonstrated 3–5x improvement in skin absorption and efficacy over conventional plant extracts
• Activates immune modulation by directing effects toward macrophages and inflammatory mediators

• Acne care and oil-control skincare
• Barrier-repairing creams and soothing serums
• Whitening and brightening products targeting pigmentation
• Formulations for mature, inflamed, or reactive skin
• Innovative delivery systems for anti-aging or immune-support cosmetics

Coix lacryma-jobi-derived nanovesicles unlock the full skincare potential of Job's tears by delivering high-performance, plant-based bioactive with precision. Ideal for brands seeking clean-label, science-driven solutions for sensitive, oily, or aging skin, this advanced ingredient bridges the gap between traditional herbal wisdom and next-generation cosmetic science.

Ready to explore the future of targeted skincare? Contact us to request samples or technical documentation.

Please kindly note that our products and services are for research use only.