LipoSwift LNP - In Vivo Spleen-Targeting Kit

The in vivo series is developed using proprietary lipid nanoparticle (LNP) technology, systematically designed to meet diverse in vivo nucleic acid application needs, achieving high delivery efficiency, precise targeting, and excellent biocompatibility. One of the key features of this series of kits is its ease of use while maintaining a high transfection efficiency. It is designed for a simple, single-step encapsulation process that does not require any specific LNP encapsulation equipment.

The LipoSwift LNP – In Vivo Spleen-Targeting Kit is a cutting-edge LNP formulation designed for the precise and efficient in vivo delivery of nucleic acids to the spleen. The spleen, a vital organ of the lymphatic system, plays a crucial role in immune response and blood filtration. Its unique function and anatomical location make it a highly desirable target for a wide range of applications, including the development of immunotherapies, vaccines, and treatments for specific blood disorders. However, delivering nucleic acids specifically to the spleen has long been a challenge, with many conventional delivery methods resulting in off-target effects and suboptimal therapeutic outcomes. Built on our proprietary in vivo LNP technology platform, this kit has been carefully engineered through fine-tuned lipid composition adjustments to achieve superior organ-specific targeting, achieving highly efficient and selective accumulation of nucleic acid payloads in the spleen. Whether you are conducting organ-specific biodistribution studies, immune cell engineering, or spleen-targeted gene therapies, this kit delivers the speed, accuracy, and reliability required for modern in vivo research.

• Exceptional Spleen-Targeting Efficacy: The primary advantage of this kit is its superior spleen-targeting ability. Through sophisticated formulation optimization, our LNP system is engineered to minimize accumulation in other organs, such as the liver, while maximizing uptake in the spleen.
• Broad Payload Compatibility: This kit is compatible with a wide variety of nucleic acids, including mRNA, siRNA, saRNA, circRNA, shRNA, etc.
• Single-Step Encapsulation Without Special Equipment: The kit enables encapsulation in one simple step using standard laboratory pipettes, drastically reducing the time and cost associated with LNP preparation.
• High Transfection Efficiency: Performance benchmarks show that LNPs prepared with this kit achieve transfection efficiencies comparable to LNPs made with professional encapsulation systems, ensuring that researchers do not compromise on data quality when opting for simplicity.
• Excellent Biocompatibility: The proprietary lipid composition of LipoSwift nanoparticles is optimized for low immunogenicity and high stability in physiological environments, ensuring minimal adverse effects and better tolerability in vivo.

Our claims are supported by robust and extensive preclinical data. Following intravenous injection of LNPs prepared with our kit, we observed a highly specific luciferase signal in the spleen.

LipoSwift LNP - In Vivo Spleen-Targeting Kit User Manual