LipoSwift LNP - In Vitro Gene Editing Kit

LipoSwift LNP - In Vitro Gene Editing Kit

The kit is an advanced, ready-to-use transfection solution built upon our proprietary lipid nanoparticle (LNP) delivery platform. This kit is specifically engineered for the highly efficient in vitro delivery of gene editing tools into a wide range of cell types. Read More

Catalog Number: ONT-LNP002

Size: 1mL; 5mL; 10mL

RNA: 50μg; 250μg; 500μg

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Description

Key Advantages

Compatible Cell Lines

Data Showcase

User Manual

The kit is a ready-to-use, advanced transfection solution developed on our proprietary lipid nanoparticle (LNP) delivery platform. It is specifically designed for the highly efficient in vitro delivery of gene editing tools into a broad range of cell types. By employing state-of-the-art LNP encapsulation technology, the kit ensures precise and low-toxicity delivery of nucleic acids directly into the cytoplasm or nucleus. Its formulation not only protects nucleic acids from degradation but also enhances cellular uptake and enables rapid intracellular release, providing a robust foundation for gene editing applications. It is worth noting that the kit has been optimized for Cas9 mRNA and guide RNA (gRNA) combinations, achieving superior editing efficiency compared to conventional transfection methods. As a result, researchers can perform faster, more reliable, and more efficient gene editing experiments with improved reproducibility.

Whether your research focuses on basic gene function studies, disease modeling, or therapeutic validation, the LipoSwift LNP – In Vitro Gene Editing Kit provides a powerful and versatile solution for accelerating your scientific discoveries.

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  • Exceptional Delivery Efficiency: The LipoSwift platform achieves industry-leading transfection efficiencies for mRNA and gRNA delivery, ensuring a high proportion of cells are successfully edited.
  • Ultra-Low Cytotoxicity: Our proprietary lipid composition minimizes cellular stress and toxicity.
  • Broad Cell Type Compatibility: LipoSwift LNP reagents are effective with both adherent and suspension cells, covering a wide spectrum of cell lines used in gene editing research.
  • Streamlined Workflow: The kit's one-step LNP encapsulation process eliminates the need for specialized equipment or lengthy optimization steps. Simply mix your nucleic acid payload with the LNP reagent within 1 min, incubate briefly, and add to cells.
  • Stable and Protective Encapsulation: The LNPs shield nucleic acids from extracellular nucleases, ensuring maximum payload integrity until cellular uptake occurs.
  • Scalable for High-Throughput Screening: Compatible with multi-well plate formats, the kit supports both small-scale proof-of-concept studies and large-scale genome-wide editing campaigns.
A-GH-MN-Z (1-9)
Cell CodeCell NameTransfection EfficiencyCell CodeCell NameTransfection EfficiencyCell CodeCell NameTransfection Efficiency
AML-12Mouse normal liver cells★★★☆HCT116Human colon cancer cell★★☆☆NCL-H460Human lung cancer cells★☆☆☆
A549Human lung cancer cells★★★★HEK293THuman embryonic kidney cells★★★★NIH/3T3Mouse embryonic fibroblasts★★★★
BHK21Hamster kidney fibroblasts★★★☆H460Human lung cancer cells★★★☆PANC-1Human epithelial cancer cells★★★☆
BT-549Human breast cancer cells★★★☆HelaHuman cervical cancer cells★★★★RAW264.7Mouse macrophages★★☆☆
B16-F0Mouse malignant melanoma cells★★★☆HepG2Human liver cancer cells★★★★SK-MEL-28Human melanoma cells★★★★
CHO-K1Chinese hamster ovary cells★★★★Hep3BHuman liver cancer cells★★★☆SW480Human colon cancer cell★★☆☆
CHO-SChinese hamster ovary cells★★☆☆JurkatHuman leukemia cells★★☆☆SW620Human colon cancer cell★☆☆☆
C2C12Mouse myofibroblasts★★★☆K562Human peripheral blood leukemia T cells★★☆☆T98GHuman glioblastoma cells★★★☆
DC2.4Mouse bone marrow-derived dendritic cells★★☆☆L6Rat skeletal muscle cells★★☆☆THP-1Human peripheral blood mononuclear cell★★☆☆
L939Mouse fibrosarcoma cells★☆☆☆VeroMonkey kidney cells★★★☆
MCF-7Human breast cancer cells★★★☆4T1Mouse breast cancer cells★★★★
MC38Mouse colon cancer cells★★★☆

Our products and services are for research use only and cannot be used for any clinical purposes.

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