LipoSwift LNP - In Vitro Cell Transfection Kit

LipoSwift LNP - In Vitro Cell Transfection Kit

The kit is developed using our proprietary lipid nanoparticle platform technology, the kit offers a powerful alternative to traditional lipid-based or electroporation methods for introducing mRNA, siRNA, and other nucleic acids into a variety of cell types. Read More

Catalog Number: ONT-LNP001

Size: 1mL; 5mL; 10mL

RNA: 50μg; 250μg; 500μg

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Description

Key Advantages

Compatible Cell Lines

Data Showcase

User Manual

The LipoSwift LNP – In Vitro Cell Transfection Kit is an advanced, ready-to-use lipid nanoparticle (LNP) delivery system designed for highly efficient and low-toxicity nucleic acid transfection in cells. Developed using our proprietary lipid nanoparticle platform technology, the kit offers a powerful solution for introducing mRNA, siRNA, and other nucleic acids into a variety of cell types (such as HEK293, HeLa, 293T, etc.). The kit is fully compatible with both suspension and adherent cell cultures, making it a versatile choice for various experimental setups.

Our patented LNP formulation ensures that the nucleic acid cargo is rapidly encapsulated within stable, biocompatible nanoparticles, allowing for safe and effective intracellular delivery. The unique design of this kit enables high transfection efficiency while minimizing cellular stress and toxicity. As a result, researchers can achieve reliable gene expression or gene silencing outcomes without compromising cell health or experimental reproducibility. Moreover, unlike many complex transfection systems, the LipoSwift LNP – In Vitro Cell Transfection Kit is remarkably easy to use. The encapsulation of nucleic acids into LNPs can be completed in a single step without the need for sophisticated instruments.

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  • High Transfection Efficiency: Our LNP formulation is optimized for rapid cellular uptake and efficient endosomal escape, enabling robust delivery of mRNA, siRNA, and other nucleic acids into target cells.
  • Extremely Low Cytotoxicity: The LipoSwift kit's formulation has been meticulously optimized to minimize cellular damage. It achieves a delicate balance between effective delivery and gentle treatment, resulting in minimal impact on cell proliferation and overall vitality.
  • Broad Cell Type Compatibility: The kit is designed to work seamlessly with both adherent and suspension cells, as well as hard-to-transfect lines. It supports a wide range of mammalian cells without the need for cell-specific optimization.
  • One-Step Encapsulation Process: Traditional LNP preparation often involves multi-step mixing or specialized microfluidic equipment. With LipoSwift, the encapsulation process is simplified to a single step, completed within one minute. Researchers only need to mix their nucleic acid payload with the LNP reagent to form delivery-ready nanoparticles.
  • No Specialized Equipment Required: All necessary reagents for nanoparticle assembly and cell transfection are included in the kit, allowing users to work directly in standard cell culture environments.
  • Reproducible Results: The formulation stability and controlled particle size distribution ensure consistent performance across experiments. This reduces variability, making it easier to compare results and draw reliable conclusions.
  • Scalable for Different Experimental Needs: Whether you are conducting small-scale exploratory studies or larger-scale high-throughput screening, the kit can be scaled accordingly without compromising efficiency or viability.
A-GH-MN-Z (1-9)
Cell CodeCell NameTransfection EfficiencyCell CodeCell NameTransfection EfficiencyCell CodeCell NameTransfection Efficiency
AML-12Mouse normal liver cells★★★☆HCT116Human colon cancer cell★★☆☆NCL-H460Human lung cancer cells★☆☆☆
A549Human lung cancer cells★★★★HEK293THuman embryonic kidney cells★★★★NIH/3T3Mouse embryonic fibroblasts★★★★
BHK21Hamster kidney fibroblasts★★★☆H460Human lung cancer cells★★★☆PANC-1Human epithelial cancer cells★★★☆
BT-549Human breast cancer cells★★★☆HelaHuman cervical cancer cells★★★★RAW264.7Mouse macrophages★★☆☆
B16-F0Mouse malignant melanoma cells★★★☆HepG2Human liver cancer cells★★★★SK-MEL-28Human melanoma cells★★★★
CHO-K1Chinese hamster ovary cells★★★★Hep3BHuman liver cancer cells★★★☆SW480Human colon cancer cell★★☆☆
CHO-SChinese hamster ovary cells★★☆☆JurkatHuman leukemia cells★★☆☆SW620Human colon cancer cell★☆☆☆
C2C12Mouse myofibroblasts★★★☆K562Human peripheral blood leukemia T cells★★☆☆T98GHuman glioblastoma cells★★★☆
DC2.4Mouse bone marrow-derived dendritic cells★★☆☆L6Rat skeletal muscle cells★★☆☆THP-1Human peripheral blood mononuclear cell★★☆☆
L939Mouse fibrosarcoma cells★☆☆☆VeroMonkey kidney cells★★★☆
MCF-7Human breast cancer cells★★★☆4T1Mouse breast cancer cells★★★★
MC38Mouse colon cancer cells★★★☆

Our products and services are for research use only and cannot be used for any clinical purposes.

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