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Oligonucleotide therapeutics are emerging forms of drugs, which consist of modified or unmodified short nucleic acid molecules, including antisense oligonucleotides (ASOs), small interfering RNA (siRNAs), microRNA (miRNAs), aptamers, and others. The mechanism of action of oligonucleotide therapeutics mainly relies on Watson-Crick base pairing to targeted mRNAs, resulting in either gene silencing, a steric block, or altered splicing patterns, with the exception of aptamers, which recognize targets by their three-dimensional structures[1]. Globally, many companies are developing oligonucleotide therapeutics to treat diseases that were untreatable previously, or to develop more effective and safer drugs for diseases that are currently treatable.
Alfa Chemistry is a biopharmaceutical company with unique insights into the mechanisms of action, chemical modifications, and delivery systems of oligonucleotide therapeutics. The oligonucleotide therapeutics we are developing are mainly targeting rare diseases, liver diseases, eye diseases, cardiovascular diseases, and cancers. We provide you with relevant technology and services to reduce your research and development time and costs. If you encounter difficulties when you develop similar drugs, or you want to convert your patent, please contact us. We are happy to help you.
Alfa Chemistry is dedicated to the development of oligonucleotide therapeutics to alleviate the suffering of patients with rare diseases.
Alfa Chemistry is developing products for the treatment of hepatitis B, non-alcoholic steatohepatitis, and primary hepatic.
Oligonucleotide therapeutics are recognized as potential treatments for many eye diseases. We have made significant progress in developing products for the treatment of NAION and glaucoma.
Alfa Chemistry hopes that our oligonucleotide therapeutics can benefit cardiovascular patients around the world. The drugs we are developing are primarily for type 2 diabetes, hyperlipidemia, and more.
Conventional therapies for cancer are often accompanied by serious adverse effects. Oligonucleotide therapeutics have the potential to change this dilemma.
Our raw materials are a strong support for product development
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Our products and services are for research use only and cannot be used for any clinical purposes.