| Catalog Number | NZs68268 |
| CAS | 68-26-8 |
| Structure |  |
| Description | Retinol, also known as vitamin A alcohol, is the major circulating form of vitamin A. It is biologically inactive. Retinol, also known as all-trans retinol, is a 20-carbon molecule with a cyclohexenyl ring, a side chain with four double bonds (in the trans configuration), and an alcohol terminal group. |
| Synonyms | all-trans-Retinol |
| Molecular Weight | 286.46 |
| Molecular Formula | C20H30O |
| Purity | 95% |
| Application | Synthesis of all-trans-retinoic acid in HepG2 cells. Studying the effects of retinol on the growth of normal mouse colon cells cultured as organoids. Determining vitamin A standards in cells. Defining culture medium components for in vitro testicular organ culture and spermatogenesis. |
| Biochem Physiol Actions | Retinol is the precursor of the active retinoid. It is converted to retinal and then to retinoic acid. All-trans and 9-cis-retinoic acid are ligands for the nuclear receptors retinoic acid receptor (RAR) and retinoid X receptor (RXR). These receptors are transcriptional regulators of various genes. Retinol and its derivatives have anti-aging properties. They also act as anti-wrinkle agents. However, due to photolability and skin irritation, they are not widely used in cosmetic formulations. Retinol can be used to treat skin conditions, including photoaging. Its deficiency has been linked to the development of xerosis and follicular hyperkeratosis. |
| MDL Number | MFCD00001552 |
| Precautionary Statements | P270 P330 P501 P280 P321 P203 P318 P405 P301+P317 P302+P352 P332+P317 P362+P364 P264+P265 P305+P351+P338 P337+P317 |
| Specification | ~2700U/mg |
| Storage Conditions | Please store this product at -20℃. |
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