Catalog NumberNZs000944
CategoryZymogens
| Description | Human Pepsinogen II is a proenzyme form of pepsin C, secreted by gastric chief and mucous neck cells. It shares structural similarity with Pepsinogen I but exhibits a broader distribution in gastric and duodenal tissues. The protein remains inactive until converted to pepsin C in acidic conditions. For research use only. Not intended for human or therapeutic use. |
| Synonyms | Pepsinogen C, Pepsinogen II, PG II, PGC |
| Molecular Weight | 40000+ |
| Purity | > 90% by SDS-PAGE |
| Appearance | White to off-white powder |
| Application | Applied in studies of gastrointestinal disorders, Helicobacter pylori infection, and gastric mucosal pathology. Also used in comparative enzymology and protein activation research. |
| Biochemical/Physiological Action | Upon activation by gastric acid, Pepsinogen II forms pepsin C, which hydrolyzes peptide bonds during digestion. The serum ratio of Pepsinogen I to II reflects gastric mucosal status and is a clinical indicator of gastric function. |
| Storage Conditions | It is recommended to store this product at -20°C. |
Please kindly note that our products and services are for research use only.
Alfa Chemistry offers a wide range of nanozymes to help customers succeed in their scientific research. Your inquiries are welcome.
Privacy Policy | Cookie Policy | Copyright © 2026 Alfa Chemistry. All rights reserved.