Catalog NumberNZs000941
CategoryZymogens
| Description | Human PAI-2 is a serine protease inhibitor mainly expressed in monocytes, macrophages, and placenta. It modulates fibrinolysis and inflammatory responses. For research use only. Not intended for human or therapeutic use. |
| Synonyms | Plasminogen Activator Inhibitor-2, Urokinase Inhibitor |
| Molecular Weight | 60 kDa |
| Purity | ≥95% by SDS-PAGE |
| Appearance | White to off-white powder |
| Application | Applied in studies of inflammation, pregnancy, and tumor invasion. Also used to investigate intracellular protease inhibition and immune modulation. |
| Biochemical/Physiological Action | PAI-2 inhibits uPA and tPA, reducing plasmin generation. It plays protective roles in inflammation and cellular stress and contributes to immune regulation and tissue remodeling. |
| Storage Conditions | It is recommended to store this product at -20°C. |
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