CAS 58-85-5 Biotin - Nanozymes / Alfa Chemistry

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Biotin

Catalog Number	NZs58855
CAS	58-85-5
Structure
Description	Biotin is a water-soluble vitamin. Mammals depend on biotin via plant and microbial dietary sources. Biotin consists of two rings that are attached to valeric acid moiety as a side chain. One of the rings is attached to ureido group and the other ring is the tetrahydrothiophene group.
Synonyms	D-Biotin, Coenzyme R, Vitamin B7, Vitamin H
Molecular Weight	244.31
Molecular Formula	C10H16N2O3S
Canonical SMILES	[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=O)N2
Melting Point	mp: 231-233 °C (lit.)
Purity	≥99% (HPLC)
Solubility	ammonium hydroxide: 50 mg/mL (2 M)
Appearance	lyophilized powder
Application	Biotin can be used to elute proteins from avidin/streptavidin resins. Biotin has been used to: culture oligodendrocytes; as a vitamin supplement for the growth of Bacillus species; and to block endogenous biotin during immunohistological procedures.
Beilstein	86838
Biochem Physiol Actions	The biotin-(strept)avidin system is essential in a variety of applications. Biotin also serves as a cofactor/coenzyme for carboxylases such as pyruvate carboxylase, acetyl-CoA carboxylases 1 and 2, 3-methylcrotonyl-CoA carboxylase (MCC), and propionyl-CoA carboxylase (PCC). It catalyzes the formation of oxaloacetate from pyruvate and carbon dioxide. Biotin conjugated to avidin or streptavidin facilitates linking target molecules (antibodies, nucleotides, protein A, etc.) to labeling systems (enzymes, fluorescent or chemiluminescent probes).
Biological Source	synthetic (organic)
Color	white to off-white
EC Number	200-399-3
MDL Number	MFCD00005541
NACRES	NA.21
Storage Conditions	Please store this product at 2-8°C.

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