Catalog NumberNZs79183190
CAS Number79183-19-0
CategoryEnzyme Activators
| Description | Cytochrome C-dependent caspase activator |
| Synonyms | 1-[(3,4-Dichlorophenyl)methyl]-1H-indole-2,3-dione |
| Molecular Weight | 306.14 |
| Molecular Formula | C15H9Cl2NO2 |
| Canonical SMILES | ClC1=CC=C(CN2C(=O)C(=O)C3=CC=CC=C23)C=C1Cl |
| InChI Key | KGRJPLRFGLMQMV-UHFFFAOYSA-N |
| Purity | >99% |
| Solubility | Soluble in ethanol (5mM) or DMSO (100mM) |
| Application | Induces PARP cleavage, DNA fragmentation; apoptotic and anti-cancer activity |
| Storage | We recommend storing this product at 4 °C. |
| Mechanism | Enhances Apaf-1 oligomerization; activates caspase-3 via caspase-9 |
| Packaging | 50mg |
| Recommended Usage | We strongly recommend preparing and using the solution on the same day. If storage is necessary, keep the solution at -20 °C for up to one month. Before use, allow the solution to equilibrate to room temperature and ensure that it is free of any precipitate. |
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