Catalog NumberNZs100938101
CAS Number100938-10-1
CategoryEnzyme Inhibitors
| Description | Slow, tight-binding, competitive aminopeptidase inhibitor |
| Synonyms | [(2S,3R)-3-Amino-2-hydroxy-5-methyl-hexanoyl]-Val-Val-Asp-OH Hydrochloride |
| Molecular Weight | 511.01 |
| Molecular Formula | C21H38N4O8.HCl |
| Canonical SMILES | [Cl-].CC(C)C[C@@H](N)[C@H](O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(O)=O.[H+] |
| InChI Key | GBDUPCKQTDKNLS-PORDUOSCSA-N |
| Purity | >98% |
| Solubility | Soluble in aqueous buffers, and in ethanol |
| Application | Slightly inhibits angiotensin III formation; completely inhibits Suc-Ala-Ala-Pro-Leu-pNA cleavage |
| Storage | We recommend storing this product at 4 °C. |
| Mechanism | Targets leucine aminopeptidases, AP-M, AP-A, AP-N, tyrosine aminopeptidase; weak SIV-PR inhibitor; moderate mitochondrial intermediate peptidase inhibitor |
| Packaging | 5mg |
| Recommended Usage | We strongly recommend preparing and using the solution on the same day. If storage is necessary, keep the solution at -20 °C for up to one month. Before use, allow the solution to equilibrate to room temperature and ensure that it is free of any precipitate. |
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