Carbon-Based Nanozymes

Carbon-Based Nanozymes

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Carbon-Based Nanozymes

Introduction

Carbon-Based Nanozymes

As a new class of nanozymes for biochemical reactions, carbon-based nanozymes have a high operational stability and low cost than natural enzymes. Meanwhile, they are facilely prepared and have great robustness against stringent conditions. More importantly, the inherent electronic properties and broad absorption spectra of carbon materials confer excellent optical or acoustic response properties to carbon-based nanozymes, allowing them to exhibit great potential for biomedical applications.

Applications

Carbon-based nanozymes possess the unique optical, electronic, thermal, acoustic and magnetic properties, which contribute to being widely used in biomedicine, such as biosensing, bioimaging, antibacterial and environmental engineering.

  • Biosensing. In light of the enzyme-like catalytic properties, carbon-based nanozymes are widely used in the field of biosensing, which exhibit high efficiency, high sensitivity and outstanding selectivity. Carbon-based nanozymes can be used to detect H2O2, glucose, acetylcholinesterase (AChE), choline oxidase (ChOx), cholesterol oxidase (COx), and D-amino acids oxidase(DAAO). Carbon-based nanozymes can also detect phenolic compounds such as catechol, resorcinol and hydroquinone, dopa, ascorbic acid (AA), glutathione (GSH), cysteine (Cys), dopamine (DA), uric acid and other small molecules. In addition, carbon-based nanozymes can also be used for the detection of ions (such as copper ions, mercury ions, lead ions and silver ions) and disease biomarkers.
Biosensing
Bioimaging
  • Bioimaging. Carbon-based nanozymes with photoluminescent and enzyme-like properties have been widely exploited for bioimaging. For example, an exosome-like carbon-based nanozyme vesicle can be used as a contrast agent for photoacoustic imaging (PAI), and used for in vivo H2O2-responsive PAI of nasopharyngeal carcinoma (NPC)[1].
  • Antibacterial. Carbon-based nanozymes with peroxidase-like activity were able to catalyze the decomposition of H2O2 into ·OH radicals, which could cause the oxidation of cellular components and induce the bacteria apoptosis. They have good antibacterial effects against both Gram-negative (Escherichia coli) and Gram-positive (Staphylococcus aureus) bacteria.
Antibacterial
Environmental Engineering
  • Environmental Engineering. Carbon-based nanozymes are environmentally friendly and show great application potential in environmental engineering. Carbon-based nanozymes can be used to degrade dyes such as methyl red, methyl orange, rhodamine B, methylene blue, phenolic compounds, orange II, etc.

Alfa Chemistry offers a series of carbon-based nanozymes. As a group of well-developed nanozymes, carbon-based nanozymes have shown tremendous potential for a broad range of biomedical applications, including biosensing, bioimaging and antibacterial. They also show great application potential in the field of environmental engineering. You can click on our product list for a detailed view. At the same time, we also offer product customization according to customer's detailed requirements. If you are interested in our products or have any questions or needs, please feel free to contact us. We will be happy to provide you with support and services.

Reference

  1. Ding, H.; et al. Exosome-like nanozyme vesicles for H2O2-responsive catalytic photoacoustic imaging of xenograft nasopharyngeal carcinoma. Nano Lett. 2019, 19(1), 203-209.

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