General Information
- Product Name: Panaxydol
- Catalog: GINS-064
- CAS No.: 72800-72-7
- Purity: ≥ 98%
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Description
Panaxydol is a unique polyacetylene compound derived from the roots of Panax ginseng C.A. Meyer. First isolated and described in 1964, this remarkable compound has gained significant attention for its potent biological properties, particularly its anti-cancer activities.
Biological Activities of Panaxydol
Extensive research has demonstrated that Panaxydol exerts powerful anti-proliferative effects against malignant cells. It is known to inhibit cancer cell growth and induce apoptosis through several intricate signaling mechanisms, including:[1]
- [Ca(2+)](i) increase: Modulating intracellular calcium levels.
- JNK and p38 MAPK activation: Regulating key signaling pathways involved in cellular stress responses.
- cAMP and MAP kinase pathways: Contributing to apoptosis and cell differentiation.
- ROS generation: Inducing reactive oxygen species (ROS) production via NADPH oxidase and mitochondrial pathways.
Furthermore, Panaxydol promotes differentiation in C6 glioma cells, potentially via a PI 3-K-dependent pathway, underscoring its therapeutic potential in cancer treatment.
Alfa Chemistry's High-Quality Panaxydol
At Alfa Chemistry, we are dedicated to delivering the highest quality Panaxydol to meet the diverse demands of both research and industrial applications. Our product is manufactured under stringent quality standards, ensuring superior performance, consistency, and reliability.
| Items | Specification |
| CAS No. | 72800-72-7 |
| Formula | C17H24O2 |
| Molecular Weight | 260.4 g/mol |
| Purity | ≥ 98% |
| Type of Compound | Aliphatic Compounds |
| Appearance | Oil |
| Source | The roots of Panax ginseng C. A. Mey. |
| Solubility | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO, acetone, etc. |
| Shelf life | Up to 24 months (2-8 °C) |
Why Choose Alfa Chemistry
- Expertise and Innovation: With over two decades of experience in research and development, Alfa Chemistry excels in the production and supply of high-purity compounds.
- Comprehensive Technical Support: We provide unparalleled technical support to help our customers maximize the benefits of our products.
- Tailored Solutions: In addition to Panaxydol, we offer a wide range of ginsenosides and related compounds, designed to fulfill the specific requirements of your projects.
For high-purity Panaxydol you can trust, Alfa Chemistry is your ideal partner. Your satisfaction is our top priority. Don't hesitate to reach out to our team to learn more about our products and services.
Reference
- Kim J Y, et al. Panaxydol induces apoptosis through an increased intracellular calcium level, activation of JNK and p38 MAPK and NADPH oxidase-dependent generation of reactive oxygen species. Apoptosis, 2011, 16: 347-358.
Please kindly note that our products and services are for research use only.
