General Information
- Product Name: Panaxadiol
- Catalog: GINS-057
- CAS No.: 19666-76-3
- Purity: ≥ 98%
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Description
Panaxadiol is a notable compound with multifaceted therapeutic properties, prominently recognized for its inhibitory effects on the hepatitis B virus. Additionally, it exhibits significant anticancer, cardioprotective, anti-arrhythmic, and antioxidative activities. A key aspect of Panaxadiol's action is its ability to inhibit Ca2+ channels, resulting in a reduced duration and probability of these channels being open, thereby demonstrating considerable anti-arrhythmic potential. In cancer research, Panaxadiol selectively disrupts the cell cycle in human cancer cell lines. It efficiently inhibits DNA synthesis, with IC50 values between 0.8 to 1.2 μM in SK-HEP-1 and HeLa cells. This compound achieves cell cycle arrest at the G1/S phase by selectively elevating p21WAF1/CIP1 levels, which subsequently down-regulates Cyclin A–Cdk2 activity, highlighting its potential as a targeted cancer therapy.
Alfa Chemistry offers premium quality Panaxadiol, featuring the following properties:
Items | Specification |
CAS No. | 19666-76-3 |
Formula | C30H52O3 |
Molecular Weight | 460.73 g/mol |
Appearance | White powder |
Purity | ≥ 98% |
Source | The roots of Panax ginseng |
Solubility | Soluble in DMSO, ethyl acetate, chloroform, dichloromethane, acetone, etc. |
Shelf life | Up to 24 months (2-8 °C) |
Alfa Chemistry is a trusted global supplier of premium ginsenosides, including high-quality Panaxadiol. We are dedicated to supporting researchers and industries worldwide by delivering exceptional products and services tailored to their needs. Our commitment extends across various fields, such as pharmaceuticals, nutraceuticals, and natural product chemistry, ensuring researchers and developers receive reliable solutions for their innovative work.
Please kindly note that our products and services are for research use only.