General Information
- Product Name: Ginsenoside Ro
- Catalog: GINS-012
- CAS No.: 34367-04-9
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Description
Ginsenoside Ro (G-Ro) is a highly abundant OA (oleanolic acid)-type ginsenoside derived and isolated from Panax ginseng C.A. Meyer.
Ginsenoside Ro exerts multiple biological activities including but not limited to anti-photoaging, anti-complementary, anti-inflammatory, anti-hepatitic, anti-diabetogenic, and hair re-growth promoting activities [1]. Specially, Ginsenoside Ro can inhibit LPS488 binding to cell membranes, suppresse the transcription and secretion levels of TNF-a, IL-6 and IL-1b. Moreover, the phosphorylation of NF-kB and MAPKs as well as the p65 subunit nuclear translocation can be inhibited by Ginsenoside Ro dose-dependently [2]. It also can exhibit a Ca2+-antagonistic antiplatelet effect and reduce the production of TXA2 and the activities of COX-1 and TXAS.
Alfa Chemistry provides high-quality Ginsenoside Ro with the properties showed below:
| Items | Specification |
| CAS No. | 34367-04-9 |
| Formula | C48H76O19 |
| Molecular Weight | 957.11 |
| Appearance | Solid |
| Purity | 98+% |
| Storage | Keep in a refrigerated, sealed, dark place |
| Solubility | DMSO: 100 mg/mL |
| Shelf life | 3 years @ -20°C in powder
2 years @ 4°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Zheng, S., Xiao, S., Wang, J., et al. Inhibitory Effects of Ginsenoside Ro on the Growth of B16F10 Melanoma via Its Metabolites. Molecules, 2019, 24(16), 2985.
- Xu, H.-L., Chen, G.-H., Wu, Y.-T., et al. Ginsenoside Ro, an oleanolic saponin of Panax ginseng, exerts anti-inflammatory effect by direct inhibiting toll like receptor 4 signaling pathway. Journal of Ginseng Research.2021.
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