General Information
- Product Name: Ginsenoside Rk3
- Catalog: GINS-024
- CAS No.: 364779-15-7
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Description
Ginsenoside Rk3 (G-Rk3) is an important and rare saponin in heat-treated ginseng, which is generated from Ginsenoside Rg1 and has a smaller molecular weight.
Ginsenoside Rk3 appears to be promising compound that could prove useful for potential anti-type 2 diabetes mellitus (T2DM), antitumor effect, anticancer, anti-anemia effect, etc. For instance, Ginsenoside Rk3 mediates hepatic gluconeogenesis and lipid accumulation via activating the AMPK/Akt signaling pathway in HFD/STZ induced T2DM mice [1]; Ginsenoside Rk3 inhibits liver injury, fibrosis and cirrhosis. Meanwhile, it reduces the inflammatory response by decreasing the expression of inflammatory cytokines, inducing apoptosis, and blocking the cell cycle [2]; in addition, it significantly inhibits TNF-α-induced NF-κB transcriptional activity.
Alfa Chemistry provides high-quality Ginsenoside Rk3 with the properties showed below:
| Items | Specification |
| CAS No. | 364779-15-7 |
| Formula | C36H60O8 |
| Molecular Weight | 620.86 |
| Appearance | Solid |
| Purity | 95+% |
| Storage | Keep in a refrigerated, sealed, dark place |
| Solubility | DMSO: 100 mg/mL |
| Shelf life | 3 years @ -20°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Liu Y, Deng J, Fan D. Ginsenoside Rk3 ameliorates high-fat-diet/streptozocin induced type 2 diabetes mellitus in mice via the AMPK/Akt signaling pathway. Food Funct. 2019 May 22;10(5):2538-2551.
- Qu L, Ma X, Fan D. Ginsenoside Rk3 Suppresses Hepatocellular Carcinoma Development through Targeting the Gut-Liver Axis. J Agric Food Chem. 2021 Sep 8;69(35):10121-10137.
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