General Information
- Product Name: Ginsenoside Rh3
- Catalog: GINS-019
- CAS No.: 105558-26-7
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Description
Ginsenoside Rg3 (G-Rg3), a triterpenoid saponin, is a bacterial metabolite of ginsenoside Rg5, which consists of a tetracyclic triterpenoid aglycon and a glycoside.
Recent studies have shown that Ginsenoside Rh3 possesses a variety of beneficial properties such as anti-inflammatory, antioxidant damage, anti-apoptotic, anti-cancer and anti-tumor effects. For example, Ginsenoside Rh3 exerts anti-inflammatory effects in microglia by regulating the 5′-adenosine monophosphate-activated protein kinase signaling pathway; it protects retinal pigment epithelial cells and retinal ganglion cells from UV by activating Nrf2. It inhibits GM-CSF expression in UVB-irradiated keratinocytes; it also has a renoprotective effect by inhibiting JNK and ERK mitogen-activated protein kinase signaling. [1,2].
Alfa Chemistry provides high-quality Ginsenoside Rh3 with the properties showed below:
| Items | Specification |
| CAS No. | 105558-26-7 |
| Formula | C36H60O7 |
| Molecular Weight | 604.86 |
| Appearance | Solid |
| Purity | 98+% |
| Storage | keep in a refrigerated, sealed, dark place |
| Solubility | DMSO: 6.67 mg/mL |
| Shelf life | 3 years @ -20°C in powder
2 years @ 4°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Cong, Z., Zhao, Q., Yang, B., et al. Ginsenoside Rh3 Inhibits Proliferation and Induces Apoptosis of Colorectal Cancer Cells. Pharmacology, 2019, 105(5-6), 329–338.
- Wang XM, She C, Li Q, et al. Ginsenoside Rh3 activates Nrf2 signaling and protects endometrial cells from oxygen and glucose deprivation-reoxygenation. Aging (Albany NY). 2020 Apr 7;12(7):6109-6119.
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