General Information
- Product Name: Ginsenoside Rh1
- Catalog: GINS-017
- CAS No.: 63223-86-9
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Description
Ginsenoside Rh1 (G-Rh1) is one of the major ginsenosides extracted from red ginseng. In addition, it has been found that after oral administration of ginseng extract, the pro-ginsenoside type ginsenosides are mainly hydrolyzed or metabolized in the gastrointestinal tract to Ginsenoside Rh1.
Ginsenoside Rh1 exhibits the potent characteristics of anti-inflammatory, antioxidant, immunomodulatory effects, and positive effects on the nervous system. For instance, Ginsenoside Rh1 prevents migration and invasion through mitochondrial ROS-mediated inhibition of STAT3/NF-κB signaling in MDA-MB-231 cells. Rh1 inhibits the Ang II-induced migration and proliferation of RASMCs by suppressing the ROS-mediated ERK1/2/p90RSK signaling pathway. Furthermore, it inhibits the expression of PPAR-γ, TNF-α, IL-6, and IL-1β [1,2].
Alfa Chemistry provides high-quality Ginsenoside Rh1 with the properties showed below:
| Items | Specification |
| CAS No. | 63223-86-9 |
| Formula | C36H62O9 |
| Molecular Weight | 638.87 |
| Appearance | Solid |
| Purity | 97+% |
| Storage | Store at 4°C |
| Solubility | DMSO: 100 mg/mL
Water: Insoluble |
| Shelf life | 3 years @ -20°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Jin Y, Huynh DTN, Myung CS, Heo KS. Ginsenoside Rh1 Prevents Migration and Invasion through Mitochondrial ROS-Mediated Inhibition of STAT3/NF-κB Signaling in MDA-MB-231 Cells. International Journal of Molecular Sciences. 2021 Sep;22(19):10458.
- Huynh DTN, Jin Y, Van Nguyen D, Myung C-S, Heo K-S. Ginsenoside Rh1 Inhibits Angiotensin II-Induced Vascular Smooth Muscle Cell Migration and Proliferation through Suppression of the ROS-Mediated ERK1/2/p90RSK/KLF4 Signaling Pathway. Antioxidants. 2022; 11(4):643.
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