General Information
- Product Name: Ginsenoside Rd
- Catalog: GINS-010
- CAS No.: 52705-93-8
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Description
Ginsenoside Rd is one of the main active components of ginseng. Its content varies among different wild ginsengs and ginseng parts, ranging from 0.02% ~ 1.66%. In addition, microbial enzymatic conversion has also become the main conversion method of Ginsenoside Rd due to its unique selectivity, mild reaction conditions and environmental compatibility (see figure 1) [1].
Ginsenoside Rd has been reported to have various biological activities, including antioxidative, anti-inflammatory, neuroprotective, anticancer, anti-metastatic, cardioprotective, and immunomodulatory activities. For instance, Chen [2] et al. found that the general effects of Ginsenoside Rd are anti-inflammatory, antioxidant, anti-apoptotic, inhibition of Ca2+ in-flux and protection of mitochondria, and through these pathways it can inhibit excitotoxicity, regulate nerve growth factor and promote nerve regeneration. In addition, it can inhibit TNF-α-induced NF-κB transcriptional activity, inhibit expression of COX-2 and iNOS mRNA and iNOS promoter activity.
Fig. 1 Schematic illustration of biotransformation of major ginsenosides Rb1, Rb2, and Rc to Rd (⟶ major pathway; ⤏ minor pathway)
Alfa Chemistry provides high-quality Ginsenoside Rd with the properties showed below:
| Items | Specification |
| CAS No. | 52705-93-8 |
| Formula | C48H82O18 |
| Molecular Weight | 947.15 |
| Appearance | Solid |
| Purity | 98+% |
| Storage | Keep in a refrigerated, sealed, dark place |
| Solubility | DMSO 90mg/mL |
| Shelf life | 3 years @ -20°C in powder
2 years @ 4°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Song, X.; Wang, L.; Fan, D. Insights into Recent Studies on Biotransformation and Pharmacological Activities of Ginsenoside Rd. Biomolecules 2022, 12, 512.
- Chen YY, Liu QP, An P, Jia M, Luan X, Tang JY, Zhang H. Ginsenoside Rd: A promising natural neuroprotective agent. Phytomedicine. 2022 Jan;95:153883.
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