Ginsenoside Rb2

General Information

• Product Name: Ginsenoside Rb2
• Catalog: GINS-006
• CAS No.: 11021-13-9

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Description

Ginsenoside Rb2, a triterpene saponin originally found in species of panax ginseng, is relatively rich in panax ginseng (0.073–0.421%) and Panax quinquefolius (0.194–0.219%). Pharmacological studies indicate that Ginsenoside Rb2 shows a beneficial role of Rb2 in the prevention and treatment of immune system disease, diabetes, obesity, tumor, photoaging, virus infection and cardiovascular problems (see figure 1). For instance, Ginsenoside Rb2 can improve the immune function that is declined in CTX (cerebrotendinous xanthomatosis)-induced immunosuppressed mice, the efficacy maybe due to the regulation of related cytokine and mRNA expression. Its other underlying mechanism involves inhibiting oxidative stress, ROS generation, inflammation and apoptosis via regulation of various cellular signaling pathways and molecules, including AKT/SHP, MAPK, EGFR/SOX2, TGF-β1/Smad, SIRT1, GPR120/AMPK/HO-1 and NF-κB ^[1].

Fig. 1 Therapeutic effects of ginsenoside Rb2 in different systems and/or tissues

Alfa Chemistry provides high-quality Ginsenoside Rb2 with the properties showed below:

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