General Information
- Product Name: Ginsenoside F11
- Catalog: GINS-030
- CAS No.: 115038-42-1
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Description
Ginsenoside F11 is a natural compound that belongs to the ginsenoside family, which is found abundantly in the roots of ginseng plants. It has gained significant attention in the field of biology and pharmaceutical research due to its potential health benefits and diverse applications. Ginsenoside F11, a remarkable compound derived from ginseng plants, holds significant promise in various fields, including cancer research, cardiovascular health, neuroprotection, and immunomodulation. Its unique chemical structure and pharmacological properties make it a valuable target for further investigation and development.
Alfa Chemistry provides high-quality Ginsenoside F11 with the properties showed below:
| Items | Specification |
| Cas | 115038-42-1 |
| Molecular Formula | C42H72O14 |
| Molecular Weight | 801.03 |
| Appearance | White Powder |
| IUPAC Name | 2-[2-fluoro-4-[2-methyl-4-[3-[3-methyl-4-[(E)-4,4,4-trifluoro-3-hydroxy-3-(trifluoromethyl)but-1-enyl]phenyl]pentan-3-yl]phenyl]phenyl]acetic acid |
| SMILES | [H][C@@]1(CC[C@]2(C)[C@]1([H])[C@H](O)C[C@]1([H])[C@@]3(C)CC[C@H](O)C(C)(C)[C@]3([H])[C@H](C[C@@]21C)OC1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1OC1O[C@@H](C)[C@H](O)[C@@H](O)[C@H]1O)[C@]1(C)CC[C@@H](O1)C(C)(C)O |
| Storage | RT |
Applications
- Anti-Cancer Properties: One of the most intriguing aspects of ginsenoside F11 is its potential anti-cancer properties. Several studies have suggested that ginsenoside F11 may exert anticancer effects by inhibiting tumor growth, inducing apoptosis (programmed cell death), and suppressing angiogenesis (formation of new blood vessels to support tumor growth). These findings make ginsenoside F11 a promising candidate for cancer therapy and warrant further investigation.
- Cardiovascular Health: Ginsenoside F11 has also been associated with cardiovascular health benefits. Research has indicated that ginsenoside F11 may help lower blood pressure, reduce cholesterol levels, and improve overall cardiovascular function. These effects are attributed to its ability to enhance nitric oxide production, which promotes vasodilation and improves blood flow.
- Neuroprotective Effects: The neuroprotective properties of ginsenoside F11 have attracted significant attention in recent years. Studies have demonstrated that ginsenoside F11 can protect neuronal cells from oxidative stress, reduce inflammation in the brain, and enhance cognitive function. These findings suggest its potential application in the prevention and treatment of neurodegenerative disorders, such as Alzheimer's disease.
- Immunomodulatory Activity: Ginsenoside F11 has been shown to possess immunomodulatory activity, meaning it can regulate and modulate the immune system. It exhibits both stimulating and inhibitory effects on immune cells, depending on the context. This ability to modulate immune responses makes ginsenoside F11 a promising compound for potential applications in immunotherapy and autoimmune disease management.
Performance
The bioavailability of ginsenoside F11 is a crucial factor to consider when assessing its performance. Studies have indicated that the bioavailability of ginsenoside F11 is relatively low, mainly due to its poor solubility and limited absorption in the gastrointestinal tract.
Ginsenoside F11 has been found to exhibit synergistic effects when combined with other compounds, such as chemotherapeutic agents or other ginsenosides. These synergistic interactions can enhance the overall therapeutic efficacy and improve treatment outcomes. For example, studies have shown that the combination of ginsenoside F11 with certain chemotherapeutic drugs can potentiate their anti-cancer effects and reduce drug resistance.
The safety profile and toxicity of ginsenoside F11 are essential considerations. While ginsenosides are generally considered safe, it is crucial to determine the appropriate dosage and evaluate any potential adverse effects. Extensive preclinical and clinical studies are required to establish the safety parameters and ensure the optimal use of ginsenoside F11 in various applications.
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
Reference
- Li, Yuzhong, et al. Pharmacokinetic characterizations of ginsenoside ocotillol, RT5 and F11, the promising agents for alzheimer's disease from american ginseng, in rats and beagle dogs. Pharmacology 104.1-2 (2019): 7-20.
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