General Information
- Product Name: Ginsenoside F1
- Catalog: GINS-020
- CAS No.: 53963-43-2
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Description
Ginsenoside F1 is one of the most important components of ginseng, which can be produced by microbial or enzymatic processes. For example, Fusarium oxysporum has β-glucosidase activity and has shown the ability to convert ginsenoside Rg1 to F1. Another example is the commercially available naringinase from Penicillium decumbens, which is capable of hydrolyzing glucose and the rhamnose fraction at the C6 position to produce ginsenoside F1 from Re and Rg1 [1].
Ginsenoside F1 is known to have antiaging, antioxidant, anticancer, and keratinocyte protective effects. For instance, Ginsenoside F1-induced activation of the insulin-like growth factor 1 (IGF-1)/insulin-like growth factor 1 receptor (IGF1R) pathway to promote angiogenesis is an effective approach to alleviate cerebral ischemia, and Ginsenoside F1 is a potential agent that improves cerebrovascular function and promotes recovery from ischemic stroke [2].
Alfa Chemistry provides high-quality Ginsenoside F1 with the properties showed below:
| Items | Specification |
| CAS No. | 53963-43-2 |
| Formula | C36H62O9 |
| Molecular Weight | 638.87 |
| Appearance | White to off white powder |
| Purity | 98+% |
| Storage | Store at 4°C |
| Solubility | DMSO: 100 mg/mL |
| Shelf life | 3 years @ -20°C in powder
2 years @ 4°C in powder
6 months @ -80°C in solvent
1 month @ -20°C in solvent |
Alfa Chemistry is committed to producing high-quality ginseng extracts and ginsenosides, based on high-end R&D and production equipment, supported by domestic and international biotechnology and scientific management team. For high quality products and more information, please feel free to contact us.
References
- Wang Y, Choi KD, Yu H, et al. Production of ginsenoside F1 using commercial enzyme Cellulase KN. J Ginseng Res. 2016 Apr;40(2):121-6.
- Zhang J, Liu M, Huang M, et al. Ginsenoside F1 promotes angiogenesis by activating the IGF-1/IGF1R pathway. Pharmacol Res. 2019 Jun;144:292-305.
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