Succinyl-Gamma-Cyclodextrin - Cyclodextrin / Alfa Chemistry

Products

Our customer services representatives are available 24 hours a day, from Monday to Sunday.

Online Inquiry

* Name

Phone

* Email

Quantity

* Services & Products of Interest

Project Description

* Verification Code

Succinyl-Gamma-Cyclodextrin

INQUIRY

GET A QUOTE

Succinyl-Gamma-Cyclodextrin

Abbreviation SuGCD

Catalog CD-DR06

Cyclodextrin Type Cyclodextrin Derivatives

Packaging 1 g, 10 g

Quality Fine chemical grade

Storage Condition Store in an airtight container at room temperature.

Availability In stock

*On-demand pack size is available, please contact us for multi-kilograms pack sizes.

Product Description

Succinyl-γ-Cyclodextrin is a modified form of γ-Cyclodextrin, functionalized with succinyl groups to enhance its solubility, chemical reactivity, and complexation capabilities. This high-performance cyclodextrin derivative is engineered to meet the demanding needs of various industries, including pharmaceuticals, biotechnology, and advanced material science.

Basic Information

Molecular Formula	C₄₈H_80-nO₄₀·(C₄H₅O₃)_n
Formula Weight	1297.2+n·(100.1)
Possible Impurities	Gamma-cyclodextrin, succinic acid
Solubility (in 100 cm³ solvent, at 25 °C)	Water: >50 g, Methanol: >50 g, Chloroform:<1 g

Detailed Information

Physical & Chemical Properties

Appearance	white to slight yellow powder
Average degree of substitution (n)	2.0-5.0
Purity	>90%
Loss on drying	<10%

Impurities

Residual succinic acid	<3%
Residual gamma-cyclodextrin	<5%

Features

The introduction of succinyl groups significantly improves the water solubility of γ-Cyclodextrin, making it suitable for applications where high solubility and bioavailability are critical.
Succinyl-γ-Cyclodextrin exhibits enhanced complexation abilities with a wide range of guest molecules, including hydrophobic drugs, fragrances, and pesticides, thereby improving stability, solubility, and controlled release profiles.
As a modified natural polysaccharide, Succinyl-γ-Cyclodextrin retains the biodegradability and non-toxic nature of its parent γ-Cyclodextrin, making it suitable for use in eco-friendly and biocompatible formulations.
The succinyl groups provide additional sites for further chemical modifications, allowing customization for specific applications, such as targeted drug delivery or responsive material design.

Applications

Pharmaceuticals

Succinyl-γ-Cyclodextrin is extensively used as a drug solubilizer and stabilizer. Its ability to form inclusion complexes with poorly water-soluble drugs enhances bioavailability and controls drug release, making it an ideal excipient in oral, topical, and injectable formulations.

Biotechnology

In biotechnological applications, it serves as a complexation agent that can stabilize enzymes, proteins, and other biomolecules, enhancing their solubility and functional stability in aqueous environments.

Food and Beverage Industry

Succinyl-γ-Cyclodextrin is used to encapsulate flavors, aromas, and colors, protecting these sensitive compounds from degradation while enhancing their solubility and stability in food matrices.

Cosmetics and Personal Care

It finds application in cosmetics as a delivery system for active ingredients, improving their penetration and bioavailability in skincare formulations. It also helps in the stabilization of volatile and sensitive components in perfumes and lotions.

Environmental Remediation

Due to its high affinity for organic pollutants, Succinyl-γ-Cyclodextrin can be used in the removal of contaminants from water, including pesticides and aromatic hydrocarbons, through the formation of non-toxic inclusion complexes.

Advanced Materials

In material science, it is employed as a functional additive to improve the properties of polymers, coatings, and films. Its unique chemistry allows it to act as a molecular scaffold for developing stimuli-responsive materials and smart packaging solutions.

Related Products

Alfa Chemistry leverages over two decades of expertise in cyclodextrin chemistry to offer high-quality, customizable Succinyl-γ-Cyclodextrin tailored to your application needs. Our state-of-the-art production facilities and rigorous quality control ensure consistent performance and compliance with the highest industry standards. For more information or to request a quote, please contact us.

It should be noted that our our products and services are for research use only, not for clinical use.