Succinyl-Alpha-Cyclodextrin
INQUIRY
Succinyl-Alpha-Cyclodextrin
Abbreviation SuACD
Catalog CD-DR04
Cyclodextrin Type Cyclodextrin Derivatives
Packaging 1 g, 10 g
Quality Fine chemical grade
Storage Condition Store in an airtight container at room temperature.
Availability In stock
*On-demand pack size is available, please contact us for multi-kilograms pack sizes.
Product Description
Succinyl-alpha-cyclodextrin is a chemically modified alpha-cyclodextrin derivative designed to enhance solubility and stability of various guest molecules. With its hydrophilic succinyl groups, it significantly improves the encapsulation efficiency of poorly soluble active ingredients, making it a critical excipient in pharmaceuticals, cosmetics, and advanced material formulations.
Basic Information
| Molecular Formula | C36H60-nO30·(C4H5O3)n |
| Formula Weight | 972.9+n·(100.1) |
| Possible Impurities | Alpha-cyclodextrin, succinic acid |
| Solubility (in 100 cm3 solvent, at 25 °C) | Water: >50 g, Methanol: >50 g, Chloroform:<1 g |
Detailed Information
Physical & Chemical Properties
| Appearance | white to slight yellow powder |
| Average degree of substitution (n) | 2.0-5.0 |
| Purity | >90% |
| Loss on drying | <10% |
Impurities
| Residual succinic acid | <3% |
| Residual alpha-cyclodextrin | <5% |
Key Features and Benefits
A. Enhanced Solubility: Succinyl modification improves water solubility, allowing the formulation of compounds with low aqueous solubility profiles.
B. Superior Encapsulation: The succinyl groups provide multiple hydrogen bonding sites, enhancing guest-host interactions, leading to improved stabilization of volatile or sensitive compounds.
C. Controlled Release: Ideal for drug delivery applications, offering a tunable release profile for active pharmaceutical ingredients (APIs).
D. Biocompatibility: Non-toxic and biodegradable, making it suitable for use in pharmaceutical and personal care products.
Applications
Alfa Chemistry's succinyl-α-cyclodextrins can be used as solubilizers, stabilizers, and drug delivery enhancers to improve bioavailability and extend the shelf life of APIs. Succinyl-α-cyclodextrins also enhance the stability and performance of active ingredients in cosmetic formulations, including skin and hair care products.
In addition, succinyl-α-cyclodextrins can be used as encapsulation agents in the food industry to protect flavor, aroma, and nutrients and extend product shelf life. Due to its unique host-guest chemistry, succinyl-α-cyclodextrins facilitate the development of novel drug formulations and complexation studies.
Related Products
Alfa Chemistry offers high-purity succinyl-alpha-cyclodextrin manufactured under stringent quality control processes, ensuring reliable performance and consistency in every batch. With over two decades of expertise in cyclodextrin chemistry, we provide tailored solutions to meet your specific application needs. For more information or to request samples, please contact Alfa Chemistry.
It should be noted that our our products and services are for research use only, not for clinical use.
