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CONTACT USCatalog CD-IC02
Cyclodextrin Type Cyclodextrin inclusion complex
Packaging 10 kg, 25 kg
Storage Condition Store in a tightly sealed container away from heat and direct light, and in a cool dry place
Uses Excipient
Availability In stock
*On-demand pack size is available, please contact us for multi-kilograms pack sizes.
Salicylic acid-cyclodextrin-complex, abbreviated as salicylic acid-CD-complex, is an inclusion complex obtained by encapsulating salicylic acid into the cavity of a CD molecule.
Salicylic acid is a fat-soluble beta-hydroxy acid derived from willow bark. It can penetrate the lipid layer between the skin, dissolve acne, and reduce inflammation, thus helping to relieve acne redness and swelling. In addition, salicylic acid has the effects of exfoliating, whitening, evening skin tone, and reducing wrinkles. Salicylic acid has good anti-inflammatory and topical antibacterial effects on the skin, enabling it to be useful in skin care products to treat mild acne. It is a key ingredient in facial cleansers, shower gels, lotions, and facial masks.
The use of salicylic acid in acne treatment is beneficial, but it also has some limitations. This organic acid is slightly soluble in fats and oils, and has a low solubility in water. It is also irritating to the skin, and can thin the stratum corneum when used in high concentrations. Alcohol has been found to be a carrier that can carry salicylic acid through the stratum corneum quickly, but can cause a stinging sensation on the skin. Therefore, new dosage forms need to be developed to better exert the effects of salicylic acid.
Our products are obtained by complexing CD molecules with salicylic acid through supramolecular technology. This CD inclusion compound helps to increase the water solubility of salicylic acid, reduce the irritation of salicylic acid, and regulate the release rate of salicylic acid, thereby better exerting its efficacy. In skin care products, by controlling the release of salicylic acid molecules from the CD cavity, the effective concentration of salicylic acid can be guaranteed locally on the skin, thereby reducing irritation and toxic side effects. This mild effect allows the product to be safely used in cosmetic formulations while being effective at delivering the benefits of salicylic acid.
Appearance | White or almost white powder |
Salicylic acid content | Min. 40.0% |
Heavy metals | Max. 10 ppm |
pH (5%) | 3.0 - 5.0 |
Loss on drying | Max. 10.0% |
Total aerobic microbial count (TAMC) | Max. 1000 cfu/g |
Total yeast and mold count (TYMC) | Max. 100 cfu/g |
Escherichia coli | Not detectable |
Salicylic acid-CD-inclusion complex overcomes the problem of poor solubility of salicylic acid and greatly reduces the skin irritation caused by salicylic acid, expanding its applications. As a water-soluble product, salicyclic acid-CD complex is more useful than salicylic acid, which is not only used in cosmetics, but also in agriculture and medicine.
As one of the leading CD companies, Alfa Chemistry has a dedicated team which has accumulated extensive expertise in the field of CD chemistry. We offer a new water-soluble salicyclic acid-CD inclusion complex in multi-kilogram quantities tailored to the special needs of the cosmetic industry. We do our best to provide customers with first-class products and services. For more information, please feel free to contact us.
It should be noted that our our products and services are for research use only, not for clinical use.
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